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67073

Sigma-Aldrich

7-Methylguanine

≥98.0% (HPLC)

Synonym(s):

2-Amino-6-hydroxy-7-methylpurine, Epiguanine

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About This Item

Empirical Formula (Hill Notation):
C6H7N5O
CAS Number:
578-76-7
Molecular Weight:
165.15
Beilstein:
174245
EC Number:
209-431-0
MDL number:
MFCD00038003
UNSPSC Code:
12352005
PubChem Substance ID:
57652069
NACRES:
NA.22

Assay

≥98.0% (HPLC)

impurities

≤1% guanine

SMILES string

Cn1cnc2N=C(N)NC(=O)c12

InChI

1S/C6H7N5O/c1-11-2-8-4-3(11)5(12)10-6(7)9-4/h2H,1H3,(H3,7,9,10,12)

InChI key

FZWGECJQACGGTI-UHFFFAOYSA-N

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Related Categories

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Gábor Paragi et al.
Molecules (Basel, Switzerland), 18(1), 225-235 (2012-12-29)
The density functional theory calculations of 7-methylguanine clusters revealed that stable ring assemblies can be formed with or without anions in the center position and hexameric clusters are the most stable and most planar ones. The coordination of anions (Cl⁻
Deepali Gupta et al.
Dalton transactions (Cambridge, England : 2003), (1)(1), 73-84 (2009-12-22)
In solution, unsubstituted guanine (GH2) is in a tautomeric equilibrium between 1H,7H-keto and 1H,9H-keto forms. Upon coordination with (dien)Pt(II), N9-bound mononuclear complex is preferentially formed. With excess (dien)Pt(II), the dinuclear complex [{Pt(dien)}2(GH-N7,N9)]3+ is formed at basic pH. The X-ray crystal
Etienne Decroly et al.
Nature reviews. Microbiology, 10(1), 51-65 (2011-12-06)
In the eukaryotic cell, capping of mRNA 5' ends is an essential structural modification that allows efficient mRNA translation, directs pre-mRNA splicing and mRNA export from the nucleus, limits mRNA degradation by cellular 5'-3' exonucleases and allows recognition of foreign
Ian Mickleburgh et al.
Antiviral chemistry & chemotherapy, 19(5), 213-218 (2009-06-02)
An unusual feature of influenza viral -messenger RNA (mRNA) synthesis is its dependence upon host cell mRNAs as a source of capped RNA primers. A crucial activity of the influenza polymerase is to steal these primers by binding and cleaving
Chiang-Wen Lee et al.
Cancers, 12(9) (2020-09-10)
Cancer is one of the leading causes of premature death and overall death in the world. On the other hand, fine particulate matter, which is less than 2.5 microns in aerodynamic diameter, is a global health problem due to its
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