283967
DL-2-Amino-5-phosphonovaleric acid
98%
Synonym(s):
5-Phosphono-DL-norvaline, DL-5-Phosphononorvaline, APV
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About This Item
Empirical Formula (Hill Notation):
C5H12NO5P
CAS Number:
Molecular Weight:
197.13
Beilstein:
2446389
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
Assay
98%
form
solid
SMILES string
NC(CCCP(O)(O)=O)C(O)=O
InChI
1S/C5H12NO5P/c6-4(5(7)8)2-1-3-12(9,10)11/h4H,1-3,6H2,(H,7,8)(H2,9,10,11)
InChI key
VOROEQBFPPIACJ-UHFFFAOYSA-N
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Thomas Mager et al.
Nature communications, 9(1), 1750-1750 (2018-05-03)
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Aging, 11(14), 5140-5157 (2019-07-25)
We examined the contribution of N-methyl-D-aspartate receptor (NMDAR) subunits in the redox-mediated decline in NMDAR function during aging. GluN2A and GluN2B selective antagonists decreased peak NMDAR currents to a similar extent in young and aged animals, indicating that a shift
Ira Espuny-Camacho et al.
Neuron, 77(3), 440-456 (2013-02-12)
The study of human cortical development has major implications for brain evolution and diseases but has remained elusive due to paucity of experimental models. Here we found that human embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs), cultured
Benjamin D S Clarkson et al.
Scientific reports, 7(1), 9037-9037 (2017-08-24)
During acute neuroinflammation, increased levels of cytokines within the brain may contribute to synaptic reorganization that results in long-term changes in network hyperexcitability. Indeed, inflammatory cytokines are implicated in synaptic dysfunction in epilepsy and in an array of degenerative and
Richardson N Leão et al.
Nature neuroscience, 15(11), 1524-1530 (2012-10-09)
The vast diversity of GABAergic interneurons is believed to endow hippocampal microcircuits with the required flexibility for memory encoding and retrieval. However, dissection of the functional roles of defined interneuron types has been hampered by the lack of cell-specific tools.
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