T7375

Thionicotinamide adenine dinucleotide

≥90%

• Synonym(e): Thionicotinamide-DPN
• Lineare Formel: C₂₁H₂₇N₇O₁₃SP₂
• CAS-Nummer: 4090-29-3
• Molekulargewicht: 679.49
• NACRES: NA.51
• PubChem Substance ID: 24900446
• UNSPSC Code: 41106305
• MDL number: MFCD00079609
• Assay: ≥90%

Eigenschaften

• Quality Segment: 200
• assay: ≥90%
• storage temp.: −20°C
• SMILES string: NC(=S)C1=CC=C[N](=C1)C2OC(COP(O)(=O)OP(O)(=O)OCC3OC(C(O)C3O)n4cnc5c(N)ncnc45)C(O)C2O
• InChI: 1S/C21H28N7O13P2S/c22-17-12-19(25-7-24-17)28(8-26-12)21-16(32)14(30)11(40-21)6-38-43(35,36)41-42(33,34)37-5-10-13(29)15(31)20(39-10)27-3-1-2-9(4-27)18(23)44/h1-4,7-8,10-11,13-16,20-21,29-32H,5-6H2,(H2,23,44)(H,33,34)(H,35,36)(H2,22,24,25)
• InChI key: JFOSDPGFZXVRDA-UHFFFAOYSA-N

Beschreibung

Application

Thionicotinamide adenine dinucleotide has been used as a substrate analog in S-adenosyl-l-homocysteine (AdoHcy) hydrolases (SAHH) inhibition assay and in NAD⁺ glycohydrolase activity.

Biochem/physiol Actions

Thionicotinamide adenine dinucleotide (sNAD) is an analog of coenzyme nicotinamide adenine dinucleotide (NAD) and NADH. sNAD is a potential inhibitor of NAD⁺ kinase. NAD⁺ kinase modulates NAD levels, contributing to cytotoxicity in cancer cells.

Other Notes

Analog of NAD

Sicherheitshinweise

• Lagerklasse: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable