SRP2080

BRCA1 human

recombinant, expressed in insect cells, ≥70% (SDS-PAGE)

• Synonym(e): BRCAI, BRCC1, BROVCA1, IRIS, PNCA4, PSCP, RNF53
• UNSPSC-Code: 12352200
• NACRES: NA.26

Eigenschaften

• Biologische Quelle: human
• Rekombinant: expressed in insect cells
• Assay: ≥70% (SDS-PAGE)
• Form: frozen liquid
• Mol-Gew.: ~209 kDa
• Verpackung: pkg of 20 μg
• Lagerbedingungen: avoid repeated freeze/thaw cycles
• Konzentration: 350 μg/mL
• Farbe: clear; colorless
• NCBI-Hinterlegungsnummer: NM_007296
• UniProt-Hinterlegungsnummer: P38398
• Versandbedingung: dry ice
• Lagertemp.: −70°C
• Angaben zum Gen: human ... BRCA1(672)

Beschreibung

Biochem./physiol. Wirkung

The human BRCA1, the product of breast and ovarian cancer gene 1, is a hyperphosphorylated protein functioning as a tumor suppressor involved in both transcription regulation and DNA repair. BRCA1 associates with RAD51 and has shown to be required for transcription-coupled repair of DNA damage as well as for the repair of chromosomal double-strand breaks. Association with a human SWI/SNF-related complex has recently suggested a potential role of BRCA1 in linking chromatin remodeling to breast cancer.

Physikalische Form

Clear and colorless frozen liquid solution

Angaben zur Herstellung

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. While working, please keep sample on ice.

Sicherheitshinweise

• Lagerklassenschlüssel: 10 - Combustible liquids
• WGK: WGK 1
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable