SML3196

SU086

≥98% (HPLC)

• Synonym(e): (2E)-3-(3-Nitrophenyl)-1-(2,4,6-trimethoxyphenyl)-2-propen-1-one
• Empirische Formel (Hill-System): C₁₈H₁₇NO₆
• CAS-Nummer: 1017898-53-1
• Molekulargewicht: 343.33
• UNSPSC Code: 12352200
• NACRES: NA.77
• MDL number: MFCD03788900
• Assay: ≥98% (HPLC)
• Form: powder

Eigenschaften

• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: powder
• color: white to beige
• solubility: DMSO: 2 mg/mL, clear (warmed)
• storage temp.: 2-8°C

Beschreibung

Biochem/physiol Actions

SU086 is a cell-permeable, non-toxic, bioavailable chalcone compound that decreases HSP90 levels and impairs glycolysis. SU086 is shown to inhibit prostate cancer cell growth, migration, and invasion in vitro (10 μM) through non-androgen receptor mediated pathways. SU086 displays favorable PK profile and synergizes with enzalutamide and abiraterone to decrease prostate cancer growth in vitro and in vivo. It is a potent inhibitor of selenoprotein thioredoxin reductases (TrxRs).

cell-permeable, non-toxic, bioavailable chalcone compound that decreases HSP90 levels and impairs glycolysis

Sicherheitshinweise

• Lagerklasse: 11 - Combustible Solids
• Was ist los?: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable