SML2173

NS3861

≥98% (HPLC)

• Synonym(e): 3-(3-Bromo-2-thienyl)-8-methyl-8-azabicyclo[3.2.1]oct-2-ene, NS 3861
• Empirische Formel (Hill-System): C₁₂H₁₄BrNS
• CAS-Nummer: 216853-59-7
• Molekulargewicht: 284.22
• UNSPSC Code: 12352200
• NACRES: NA.77
• Assay: ≥98% (HPLC)
• Form: powder

Eigenschaften

• assay: ≥98% (HPLC)
• form: powder
• color: white to beige
• solubility: DMSO: 2 mg/mL, clear
• storage temp.: 2-8°C
• SMILES string: BrC1=C(SC=C1)C2=CC(N3C)CCC3C2
• InChI key: ZJCNRVHZJADROC-UHFFFAOYSA-N

Beschreibung

Biochem/physiol Actions

α3β2 heteromeric neuronal nAChRs agonist

NS3861 is a neuronal nicotinic receptor agonist that selectively activates α3 containing nAChRs and it displays higher efficacy at the α3β2 receptor compared with the α3β4 receptor. NS3861 does not activate α4 containing receptors. NS3861 was reported to reverse chronic opioid-induced constipation in vivo.

Sicherheitshinweise

• Lagerklasse: 11 - Combustible Solids
• Was ist los?: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable