SML0397

DR2313

≥98% (HPLC)

• Synonym(e): 3,5,7,8-Tetrahydro-2-methyl-4H-thiopyrano[4,3-d]pyrimidin-4-one
• Empirische Formel (Hill-System): C₈H₁₀N₂OS
• CAS-Nummer: 284028-90-6
• Molekulargewicht: 182.24
• NACRES: NA.77
• PubChem Substance ID: 329825393
• UNSPSC Code: 12352200
• MDL number: MFCD08703132
• Assay: ≥98% (HPLC)
• Form: powder

Eigenschaften

• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: powder
• color: white to beige
• solubility: H₂O: >2 mg/mL (warmed)
• storage temp.: 2-8°C
• SMILES string: CC1=NC(=O)C2=C(CCSC2)N1
• InChI: 1S/C8H10N2OS/c1-5-9-7-2-3-12-4-6(7)8(11)10-5/h2-4H2,1H3,(H,9,10,11)
• InChI key: HRYKZAKEAVZGJD-UHFFFAOYSA-N

Beschreibung

Biochem/physiol Actions

DR2313 is a PARP inhibitor.

DR2313 is a PARP-1; PARP-2 inhibitor (Ki = 0.23 mM). DR2313 has neuroprotective effects in both in vivo and in vitro ischemic models, and reduces cortical infarct volume in focal ischemia in rats.

Features and Benefits

This compound is featured on the Caspases page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Sicherheitshinweise

• Lagerklasse: 11 - Combustible Solids
• Was ist los?: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable