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Merck

PLA0097

Sigma-Aldrich

Rabbit anti-CBP Antibody, Affinity Purified

Powered by Bethyl Laboratories, Inc.

Synonym(e):

CBP, KAT3A, RSTS, RTS, Rubinstein-Taybi syndrome

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About This Item

UNSPSC-Code:
12352203
NACRES:
NA.41

Biologische Quelle

rabbit

Qualitätsniveau

Antikörperform

affinity purified immunoglobulin

Antikörper-Produkttyp

primary antibodies

Qualität

Powered by Bethyl Laboratories, Inc.

Speziesreaktivität

human

Konzentration

1 mg/mL

Methode(n)

immunoprecipitation (IP): 1-4 μg/mg
western blot: 1:1,000- 1:25,000

Hinterlegungsnummer

NP_004371.1

Versandbedingung

wet ice

Lagertemp.

2-8°C

Angaben zum Gen

rabbit ... CBP(1387)

Immunogen

The epitope recognized by PLA0097 maps to a region between residues 975 and 1025 of human CREB Binding Protein using the numbering given in entry NP_004371.1 (GeneID 1387).

Physikalische Form

Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% sodium azide

Sonstige Hinweise

CBP [cAMP response element-binding protein (CREB)-binding protein] interacts with and is a transcriptional co-activator of a multitude of transcriptional regulators that includes CREB. CBP is structurally and functionally similar to p300 but is encoded by an independent gene. CBP coactivation may be achieved through the regulation of chromatin structure due to its ability to catalyze the acetylation of histones. CBP has potential tumor suppressor properties and is important to integrating cell-signaling cues for proliferation, differentiation and apoptosis.

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Lagerklassenschlüssel

12 - Non Combustible Liquids

WGK

nwg

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable


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Yanmei Cui et al.
Oncogene, 38(27), 5516-5529 (2019-04-03)
The early recurrence of hepatocellular carcinoma (HCC) is the main obstacle for long-term survival of patients. Wnt/β-catenin signaling has been involved in the development and progression of HCC. However, the molecular changes that link Wnt/β-catenin activation and HCC early recurrence

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