O003

β-Funaltrexamine hydrochloride

Opioid receptor antagonist, solid

• Synonym(e): β-FNA hydrochloride, (E)-4-[[(5α,6β)-17-(Cyclopropylmethyl)-4,5-epoxy-3,14-dihydroxymorphinan-6-yl]amino]-4-oxo-2-butenoic acid methyl ester hydrochloride
• Empirische Formel (Hill-System): C₂₅H₃₀N₂O₆ · HCl
• CAS-Nummer: 72786-10-8
• Molekulargewicht: 490.98
• UNSPSC Code: 12352116
• PubChem Substance ID: 24897921
• NACRES: NA.77
• MDL number: MFCD10565941
• Form: solid
• Storage condition: desiccated

Eigenschaften

• Produktname: β-Funaltrexamine hydrochloride, solid
• form: solid
• drug control: regulated under CDSA - not available from Sigma-Aldrich Canada
• storage condition: desiccated
• color: white
• solubility: H₂O: 7.5 mg/mL (aqueous solutions should be promptly used), methanol: 7.6 mg/mL (do not store in ethanolic solution; methanolic solutions may be stored for several weeks at 4 °C)
• storage temp.: −20°C
• SMILES string: Cl.COC(=O)\C=C\C(=O)N[C@@H]1CC[C@@]2(O)[C@H]3Cc4ccc(O)c5OC1[C@]2(CCN3CC6CC6)c45
• InChI: 1S/C25H30N2O6.ClH/c1-32-20(30)7-6-19(29)26-16-8-9-25(31)18-12-15-4-5-17(28)22-21(15)24(25,23(16)33-22)10-11-27(18)13-14-2-3-14;/h4-7,14,16,18,23,28,31H,2-3,8-13H2,1H3,(H,26,29);1H/b7-6+;/t16-,18-,23+,24+,25-;/m1./s1
• InChI key: BIPHUOBUKMPSQR-NQGXHZAGSA-N

Beschreibung

Biochem/physiol Actions

Selective irreversible μ opioid receptor antagonist that is also a κ opioid receptor agonist.

Features and Benefits

This compound is featured on the Opioid Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Sicherheitshinweise

• Lagerklasse: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)