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N8161

Sigma-Aldrich

NS309

≥98% (HPLC), solid

Synonym(e):

3-Oxime-6,7-dichloro-1H-indole-2,3-dione

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About This Item

Empirische Formel (Hill-System):
C8H4Cl2N2O2
CAS-Nummer:
18711-16-5
Molekulargewicht:
231.04
MDL-Nummer:
MFCD06798346
UNSPSC-Code:
12352200
PubChem Substanz-ID:
329818681
NACRES:
NA.77

Assay

≥98% (HPLC)

Form

solid

Farbe

yellow

Löslichkeit

DMSO: 22 mg/mL

Lagertemp.

2-8°C

SMILES String

O\N=C1\C(=O)Nc2c(Cl)c(Cl)ccc12

InChI

1S/C8H4Cl2N2O2/c9-4-2-1-3-6(5(4)10)11-8(13)7(3)12-14/h1-2,14H,(H,11,12,13)

InChIKey

CVOUSAVHMDXCKG-UHFFFAOYSA-N

Biochem./physiol. Wirkung

NS309 is a Ca2+-activated IK/SK potassium channel activator.

Leistungsmerkmale und Vorteile

This compound is featured on the Potassium Channels page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Vorsicht

air sensitive

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 2

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

dust mask type N95 (US), Eyeshields, Gloves

Analysenzertifikate (COA)

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The aim of this study was to examine the influence of deoxycorticosterone acetate-salt (DOCA-salt) hypertension and chronic treatment with the fatty acid amide hydrolase inhibitor, URB597, on small and intermediate conductance calcium-activated potassium channels and endothelium-dependent hyperpolarization (K
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