I145

I-AB-MECA

solid

• Synonym(e): 1-[6-[[(4-Amino-3-iodophenyl)methyl]amino]-9H-purin-9-yl]-1-deoxy-N-methyl-β-D-ribofuranuronamide, 3-Iodo-4-aminobenzyl-5′-N-methylcarboxamidoadenosine, N⁶-(4-Amino-3-iodobenzyl)-5′-N-methylcarbamoyladenosine
• Empirische Formel (Hill-System): C₁₈H₂₀IN₇O₄
• CAS-Nummer: 152918-27-9
• Molekulargewicht: 525.30
• NACRES: NA.77
• PubChem Substance ID: 24895933
• UNSPSC Code: 12352200
• MDL number: MFCD00671784
• Form: solid

Eigenschaften

• form: solid
• color: off-white
• solubility: 45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: 0.2 mg/mL, DMSO: 10 mg/mL, 0.1 M NaOH: 2 mg/mL, 0.1 M HCl: 7 mg/mL, H₂O: insoluble
• storage temp.: −20°C
• SMILES string: CNC(=O)[C@H]1O[C@H]([C@H](O)[C@@H]1O)n2cnc3c(NCc4ccc(N)c(I)c4)ncnc23
• InChI: 1S/C18H20IN7O4/c1-21-17(29)14-12(27)13(28)18(30-14)26-7-25-11-15(23-6-24-16(11)26)22-5-8-2-3-10(20)9(19)4-8/h2-4,6-7,12-14,18,27-28H,5,20H2,1H3,(H,21,29)(H,22,23,24)/t12-,13+,14-,18+/m0/s1
• InChI key: LOGOEBMHHXYBID-MOROJQBDSA-N
• Gene Information: human ... ADORA3(140) ; rat ... Adora1(29290), Adora2a(25369), Adora3(25370)

Beschreibung

Biochem/physiol Actions

Reference standard for radioiodinated I-AB-MECA, a widely used, high affinity radioligand for the A₃ adenosine receptor.

Legal Information

Sold under license from the National Institutes of Health.

Sicherheitshinweise

• Lagerklasse: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)