H4397

TiterMax^® Classic Adjuvant

liquid

• Synonym(e): Adjuvant System, TiterMax Adjuvant
• NACRES: NA.46
• UNSPSC Code: 12352203

Eigenschaften

• form: liquid
• Quality Segment: 100
• availability: not available in Japan
• storage temp.: 2-8°C

Beschreibung

General description

The effectiveness of an oil emulsion vaccine greatly depends on the form and stability of the emulsion. TiterMax Classic is a water-in-oil formulation with up to 90% water and a powerful adjuvant used in many protocols. TiterMax Classic Adjuvant contains three essential ingredients: a block copolymer, CRL89-41, squalene (a metabolizable oil) and a unique microparticulate stabilizer. The emulsion is less viscous and suitable for injection through small needles.

Application

TiterMax^® Classic Adjuvant has been used to boost the production of antigen-specific polyclonal IgG in rabbits.

For mice, four doses of 10 microl each into subcutaneous or muscular sites is recommended. TiterMax^® was used in mice followed by isolation of CD4 T cells for epitope mapping[1] and to test vaccines against Neisseria species.[2]

Biochem/physiol Actions

TiterMax Classic has been especially formulated with squalene to produce stable water-in-oil emulsions with up to 90% water. It is considerably easier to emulsify TiterMax Classic than Freund′s adjuvant. The resulting emulsion is less viscous, making it easier to inject through small needles.

Legal Information

TiterMax is a registered trademark of TiterMax USA, Inc

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Sicherheitshinweise

• Lagerklasse: 10 - Combustible liquids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)