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F5384

Sigma-Aldrich

Anti-Human IgM (μ-chain specific)−FITC antibody produced in goat

affinity isolated antibody, buffered aqueous solution

Synonym(e):

Goat Anti-Human IgM (μ-chain specific)−Fluorescein isothiocyanate

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About This Item

MDL-Nummer:
MFCD00162462
UNSPSC-Code:
12352203
NACRES:
NA.46

Biologische Quelle

goat

Konjugat

FITC conjugate

Antikörperform

affinity isolated antibody

Antikörper-Produkttyp

secondary antibodies

Klon

polyclonal

Form

buffered aqueous solution

Methode(n)

direct immunofluorescence: 1:32

Lagertemp.

2-8°C

Posttranslationale Modifikation Target

unmodified

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Allgemeine Beschreibung

The product binds human IgM; but does not bind other human Igs.

Anwendung

Anti-Human IgM (μ-chain specific)-FITC antibody produced in goat was used as secondary antibody in serodiagnosis of Lyme disease based on seroreactivity against Borrelia spirochaetes.

Biochem./physiol. Wirkung

IgM antibodies are present as pentamers in the serum and are produced in response to antigens.

Physikalische Form

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 1% bovine serum albumin and 15 mM sodium azide

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Lagerklassenschlüssel

12 - Non Combustible Liquids

WGK

nwg

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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Nayoung Ko et al.
Scientific reports, 12(1), 9611-9611 (2022-06-11)
Pig-to-human organ transplantation is a feasible solution to resolve the shortage of organ donors for patients that wait for transplantation. To overcome immunological rejection, which is the main hurdle in pig-to-human xenotransplantation, various engineered transgenic pigs have been developed. Ablation
J C Magee et al.
The Journal of clinical investigation, 96(5), 2404-2412 (1995-11-01)
Immunoglobulins regulate the complement system by activating complement on foreign surfaces and diverting reactive complement proteins away from autologous cell surfaces. Based on this model, we explored the ability of Ig to balance complement activation versus control in a pig-to-primate
Julia Hennicke et al.
New biotechnology, 50, 20-26 (2019-01-11)
IgM antibodies are arousing considerable interest as biopharmaceuticals. Despite their immunotherapeutic potential, little is known about the impact of environmental conditions on product quantity and quality of these complex molecules. Process conditions influence the critical quality attributes (CQAs) of therapeutic
Clayton A White et al.
Journal of immunology (Baltimore, Md. : 1950), 193(12), 5933-5950 (2014-11-14)
Class-switch DNA recombination (CSR) and somatic hypermutation (SHM), which require activation-induced cytidine deaminase (AID), and plasma cell differentiation, which requires B lymphocyte-induced maturation protein-1 (Blimp-1), are critical for the generation of class-switched and hypermutated (mature) Ab and autoantibody responses. We
First detection and molecular identification of Borrelia garinii isolated from human skin in Taiwan.
Li-Lian Chao et al.
Journal of medical microbiology, 59(Pt 2), 254-257 (2009-11-17)
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