D3943

DAPH

≥98% (HPLC), solid

• Synonym(e): 4,5-Dianilinophthalimide, 5,6-Bis(phenylamino)-1H-isoindole-1,3(2H)-dione, CGP 52411
• Empirische Formel (Hill-System): C₂₀H₁₅N₃O₂
• CAS-Nummer: 145915-58-8
• Molekulargewicht: 329.35
• NACRES: NA.77
• PubChem Substance ID: 24724461
• UNSPSC Code: 51111800
• MDL number: MFCD00236442
• Assay: ≥98% (HPLC)
• Form: solid

Eigenschaften

• assay: ≥98% (HPLC)
• form: solid
• color: orange
• solubility: DMSO: >20 mg/mL, H₂O: insoluble
• storage temp.: 2-8°C
• SMILES string: O=C1NC(=O)c2cc(Nc3ccccc3)c(Nc4ccccc4)cc12
• InChI: 1S/C20H15N3O2/c24-19-15-11-17(21-13-7-3-1-4-8-13)18(12-16(15)20(25)23-19)22-14-9-5-2-6-10-14/h1-12,21-22H,(H,23,24,25)
• InChI key: AAALVYBICLMAMA-UHFFFAOYSA-N
• Gene Information: human ... EGFR(1956)

Beschreibung

Biochem/physiol Actions

DAPH is an inhibitor of Aβ fibril formation; Protein tyrosine kinase inhibitor, specific for EGFR.

Features and Benefits

This compound is featured on the EGFR page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Sicherheitshinweise

• Lagerklasse: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)