UM-UC-6

8090503, human bladder, Epithelial

• UNSPSC Code: 41106514
• Biological source: human bladder
• Relevant disease(s): cancer
• Growth mode: Adherent
• Karyotype: Modal number of chromosomes is 51. See reference.
• Morphology: Epithelial

Eigenschaften

• Produktname: UM-UC-6, 08090503
• biological source: human bladder
• growth mode: Adherent
• karyotype: Modal number of chromosomes is 51. See reference.
• morphology: Epithelial
• products: Not specified
• receptors: Not specified
• technique(s): cell culture | mammalian: suitable
• relevant disease(s): cancer
• shipped in: dry ice
• storage temp.: −196°C

Beschreibung

Application

Drug resistance in bladder neoplasms

Biochem/physiol Actions

Human transitional cell carcinoma of the bladder

STR-PCR Data: Amelogenin: X,Y
CSF1PO: 11
D13S317: 13,14
D16S539: 9,13
D5S818: 11,13
D7S820: 8,10
THO1: 7
TPOX: 9,11
vWA: 18

UM-UC-6 was obtained by transurethral resection of a bladder transitional cell carcinoma found in a male patient. UM-UC-6 was found to produce tumours in athymic nude mice.

Preparation Note

EMEM (EBSS) + 2mM Glutamine + 1% Non Essential Amino Acids (NEAA) + 10% Foetal Bovine Serum (FBS).

Split sub-confluent cultures (70-80%) 1:4 to 1:10 i.e. seeding at 2-4x10,000 cells/cm² using 0.05% trypsin/EDTA; 5% CO₂; 37°C. Doubling time approximately 38 hours.

Other Notes

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This cell line is part of the European Collection of Authenticated Cell Cultures (ECACC), an international repository managed by the United Kingdom Health Security Agency (UKHSA). Use of this product by commercial organizations may require a license agreement. Commercial customers will be contacted by cellscreening@merckgroup.com to provide further information after the order request is submitted. Any other use of these products is prohibited without the express written permission of UKHSA. Inquiries regarding authorized use of this cell line or its genomic DNA may be directed to culturecollections@ukhsa.gov.uk.

Disclaimer

This cell line has special release conditions: Commercial organisations are required to complete the ′Cell Line Release Authorisation for Research Use in Commercial Organisations′ release conditions form.