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Merck

C7401

Sigma-Aldrich

Anti-Lectin, Canavalia ensiformis antibody produced in rabbit

fractionated antiserum, lyophilized powder

Synonym(e):

Anti-Con A, Anti-Jack Bean Concanavalin A

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About This Item

MDL-Nummer:
UNSPSC-Code:
12352203
NACRES:
NA.46

Biologische Quelle

rabbit

Qualitätsniveau

Konjugat

unconjugated

Antikörperform

fractionated antiserum

Antikörper-Produkttyp

primary antibodies

Klon

polyclonal

Form

lyophilized powder

Speziesreaktivität

Canavalia ensiformis

Verpackung

vial of ~2 mL lyophilized antiserum

Methode(n)

indirect ELISA: 1:25,000

Lagertemp.

2-8°C

Posttranslationale Modifikation Target

unmodified

Verwandte Kategorien

Immunogen

Jack Bean Concanavalin A (Con A).

Anwendung

Anti-Lectin, Canavalia ensiformis antibody produced in rabbit has been used in:
  • enzyme-linked immunosorbent assays (ELISA)
  • immunochemistry
  • enhanced chemiluminescence ECL western blot analysis
  • western blot

Biochem./physiol. Wirkung

Concanavalin A is a lectin isolated from Canavalia ensiformis or Jack bean seeds. It has potent mitogenic effect on T cells and triggers the activity of both helper and suppressor T cells exhibiting immune regulator activity. Con A triggers autophagy by binding on the cell membrane glycoprotein and is internalized to the mitochondria. It activates immune response in liver and displays anti-hepatoma effect.

Zielbeschreibung

Lectins are highly specific carbohydrate binding proteins useful in carbohydrate and cell membrane studies, as well as cell agglutination and typing techniques.

Physikalische Form

Lyophilized from 0.01 M phosphate buffered saline, pH 7.2.

Rekonstituierung

Reconstitute with 2 mL deionized water.

Lagerung und Haltbarkeit

Prior to reconstitution store the product at 2-8 °C. After reconstitution, the solution may be stored frozen in working aliquots. Repeated freezing and thawing is not recommended. If slight turbidity occurs upon prolonged storage clarify the solution by centrifugation before use.

Rechtliche Hinweise

ECL is a trademark of Cytiva

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves, type N95 (US)


Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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Die Dokumentenbibliothek aufrufen

M Malerba et al.
Biochemical and biophysical research communications, 286(5), 984-990 (2001-08-31)
Several authors previously showed that the interaction between 14-3-3 proteins and plasma membrane H(+)-ATPase leads to an activated complex in which the enzyme is endowed with more favorable kinetic parameters and a more physiological pH optimum. In this paper we
Hai-Xia Wang et al.
World journal of gastroenterology, 18(2), 119-125 (2012-01-19)
As a chronic inflammatory disease of the liver, the pathogenic mechanisms of autoimmune hepatitis (AIH) have not yet been elucidated, with prognosis and diagnosis remaining unsatisfied. Currently the only viable treatments of AIH are immunosuppressant application and liver transplantation. It
Rong Wang et al.
Cell death & disease, 13(7), 626-626 (2022-07-20)
Castration-resistance of prostate cancer is one of the most challenging clinical problems. In the present study, we have performed proteomics and glycomics using LNCaP model. Growth differentiation factor-15 (GDF15) level is increased in androgen receptor (AR) inhibitor-resistant cells and the
B Fairburn et al.
Biochimie, 88(9), 1165-1174 (2006-05-13)
The stress protein gp96 exhibits a number of immunological activities, the majority of studies into which have used gp96 purified from a variety of tissues. On the basis of 1-D gel electrophoresis, the purity of these preparations has been reported
The use of concanavalin A to study the immunoregulation of human T cells.
J M Dwyer et al.
Clinical and experimental immunology, 46(2), 237-249 (1981-11-01)

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