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Merck

B1552

Sigma-Aldrich

Bromoenol lactone

≥98% (TLC)

Synonym(e):

BEL, E-6-(Bromoethylene)tetrahydro-3-(1-naphthyl)-2H-pyran-2-one

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5 MG
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About This Item

Empirische Formel (Hill-System):
C16H13BrO2
CAS-Nummer:
Molekulargewicht:
317.18
MDL-Nummer:
UNSPSC-Code:
41106300
PubChem Substanz-ID:
NACRES:
NA.77

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Biologische Quelle

synthetic (organic)

Assay

≥98% (TLC)

Form

powder

Wirksamkeit

636 nM Ki

Löslichkeit

DMSO: soluble (Dilute in aqueous medium immediately prior to use and store on ice for no more than 12 hours.)
degassed ethanol: soluble (Dilute in aqueous medium immediately prior to use and store on ice for no more than 12 hours.)

λmax

224 nm

Lagertemp.

−20°C

SMILES String

[H]\C(Br)=C1\CCC(C(=O)O1)c2cccc3ccccc23

InChI

1S/C16H13BrO2/c17-10-12-8-9-15(16(18)19-12)14-7-3-5-11-4-1-2-6-13(11)14/h1-7,10,15H,8-9H2/b12-10+

InChIKey

BYUCSFWXCMTYOI-ZRDIBKRKSA-N

Biochem./physiol. Wirkung

Potent, irreversible inhibitor of calcium-independent phospholipase A2 and of magnesium-dependent phosphatidate phosphohydrolase from P388D macrophages (IC50 = 8 μM); enzyme activated irreversible chymotrypsin inhibitor (Ki = 636 nM).

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Persönliche Schutzausrüstung

dust mask type N95 (US), Eyeshields, Gloves


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Artikel

Analytical Enzyme Chymotrypsin: Chymotrypsin is produced in the acinar cells of the pancreas as the inactive precursor, chymotrypsinogen.

Questions

  1. Is product B1552 the S enantiomer, the R enantiomer, or the racemic mixture of the S-R enantiomers?

    1 answer
    1. The product B1552 is supplied as a racemic mixture.

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