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Merck

930-05A

Sigma-Aldrich

Human Renal Proximal Tubular Epithelial Cells: HRPTEpC, adult

Synonym(e):

Proximal Tubular Epithelial Cells

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About This Item

UNSPSC-Code:
41106514
NACRES:
NA.81

Biologische Quelle

human kidney

Qualitätsniveau

Verpackung

pkg of 500,000 cells

Hersteller/Markenname

Cell Applications, Inc

Wachstumsmodus

Adherent

Methode(n)

cell culture | mammalian: suitable

Versandbedingung

dry ice

Lagertemp.

−196°C

Allgemeine Beschreibung

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Human Renal Proximal Tubular Epithelial Cells (HRPTEpC) provide a useful tool for studying various aspects of pathology and biology of the human renal proximal tubular cells in vitro. HRPTEpC have recently been used in a study of metabolic enzymes responding to energy depletion in renal cells. HRPTEpCs have a pivotal role in kidney function including reabsorbtion of glucose and protein, and also play a part in the glucotoxicity associated with diabetes.

Ursprung der Zelllinie

Kidney

Anwendung

Kidney disease, diabetes, glucotoxicity, pathology. kidney function, reabsorbtion of glucose and protein, biology of renal proximal tubular cells in vitro, metabolic enzymes, cell energy usage.

Verpackung

First or second passage, >500,000 cells in RenaEpi Basal Medium containing 10% FBS & 10% DMSO.

Komponenten

RenaEpi Basal Medium containing 10% FBS & 10% DMSO

Qualität

Each lot was tested for proper morphology, ability to attach and spread on tissue culture ware surface, and proliferate in RenaEpi Growth Medium, Negative for HIV, Hepatitis B, Hepatitis C, mycoplasma, bacteria, and fungi.

Sonstige Hinweise

Can be cultured at least 6 population doublings

Haftungsausschluss

RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.

Lagerklassenschlüssel

10 - Combustible liquids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable


Analysenzertifikate (COA)

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In der Dokumentenbibliothek finden Sie die Dokumentation zu den Produkten, die Sie kürzlich erworben haben.

Die Dokumentenbibliothek aufrufen

Fatimah K Khalaf et al.
Journal of the American Heart Association, 9(3), e013933-e013933 (2020-02-06)
Background Recent studies have highlighted a critical role for a group of natriuretic hormones, cardiotonic steroid (CTS), in mediating renal inflammation and fibrosis associated with volume expanded settings, such as chronic kidney disease. Immune cell adhesion is a critical step
Duygu Elif Yilmaz et al.
The Journal of biological chemistry, 298(3), 101589-101589 (2022-01-17)
Current immunosuppressive strategies in organ transplantation rely on calcineurin inhibitors cyclosporine A (CsA) or tacrolimus (Tac). Both drugs are nephrotoxic, but CsA has been associated with greater renal damage than Tac. CsA inhibits calcineurin by forming complexes with cyclophilins, whose

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