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85451

Sigma-Aldrich

β-Sitosterol

≥70%

Synonym(e):

α-Dihydrofucosterol, 22,23-Dihydrostigmasterol, 24α-Ethylcholesterin, 5-Stigmasten-3β-ol

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About This Item

Empirische Formel (Hill-System):
C29H50O
CAS-Nummer:
83-46-5
Molekulargewicht:
414.71
Beilstein:
1916165
EG-Nummer:
201-480-6
MDL-Nummer:
MFCD00003631
UNSPSC-Code:
12352211
PubChem Substanz-ID:
329769380
NACRES:
NA.77

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Biologische Quelle

plant

Assay

≥70%

Form

powder

Verunreinigungen

campesterol and β-sitostanol, residual

mp (Schmelzpunkt)

136-140 °C (lit.)

Funktionelle Gruppe

hydroxyl

SMILES String

O[C@H](C1)CC[C@@]2(C)C1=CC[C@]3([H])[C@]2([H])CC[C@@]4(C)[C@@]3([H])CC[C@]4([H])[C@H](C)CC[C@H](C(C)C)CC

InChI

1S/C29H50O/c1-7-21(19(2)3)9-8-20(4)25-12-13-26-24-11-10-22-18-23(30)14-16-28(22,5)27(24)15-17-29(25,26)6/h10,19-21,23-27,30H,7-9,11-18H2,1-6H3/t20-,21-,23+,24+,25-,26+,27+,28+,29-/m1/s1

InChIKey

KZJWDPNRJALLNS-VJSFXXLFSA-N

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Anwendung

β-Sitosterol was used to supplement diet of mice to study its effect on body mass accumulation.[1]

Biochem./physiol. Wirkung

β-Sitosterol is a plant sterol that has hypocholesterolemic activity.[2] Only 5% of β-Sitosterol is absorbed by humans. It is hypothesized that the cholesterol-lowering activity is by competing cholesterol for uptake by the cells or by interfering with the esterification of cholesterol.[3] β-Sitosterol is reported to reduce the incidence of colon tumors.[4]

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves, type N95 (US)

Hier finden Sie alle aktuellen Versionen:

Analysenzertifikate (COA)

Lot/Batch Number
BCCL2725
BCCK6133
BCCJ3218
BCCH0450
BCCG3943

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Sitostanol-5,6,22,23-d4 97 atom % D, 95% (CP)

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β-Sitosterol phyproof® Reference Substance

PHL89283

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campesterol Avanti Research™ - A Croda Brand 700126P, powder

Avanti

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β-Sitosterin-β-D-glucosid analytical standard

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β-Sitosterin-β-D-glucosid

Oliver Harlé et al.
PloS one, 15(5), e0233285-e0233285 (2020-05-27)
Fermentation by microorganisms is a key step in the production of traditional food products such as bread, cheese, beer and wine. In these fermentative ecosystems, microorganisms interact in various ways, namely competition, predation, commensalism and mutualism. Traditional wine fermentation is
P P Nair et al.
The American journal of clinical nutrition, 40(4 Suppl), 927-930 (1984-10-01)
Cholesterol and fat are implicated as dietary factors enhancing the risk for colon carcinogenesis. Plant sterols such as beta-sitosterol when added to diets of experimental animals treated with colon carcinogens reduce tumor yields and counteract the proliferative changes associated with
F J Field et al.
Journal of lipid research, 24(4), 409-417 (1983-04-01)
Rabbits were fed either 10% coconut oil, 10% coconut oil and 1% beta-sitosterol, 10% coconut oil and 1% cholesterol, or 10% coconut oil and 1% beta-sitosterol plus 1% cholesterol for 4 weeks. Microsomal membranes from intestines of animals fed the
Pauline Seguinot et al.
International journal of food microbiology, 316, 108441-108441 (2019-11-30)
Even though non-Saccharomyces yeasts were regarded as spoilage microorganisms for a long time, their abilities to improve and diversify the aromatic profile of wines are now well recognized. Consequently, their use in combination with S. cerevisiae strains during winemaking has
Yoshihide Yamanashi et al.
The Journal of pharmacology and experimental therapeutics, 320(2), 559-564 (2006-12-01)
Previous in vivo studies including those with knockout mice suggested that Niemann-Pick C1-like 1 (NPC1L1) plays an essential role in the intestinal absorption of cholesterol. To characterize the mechanism of cholesterol uptake mediated by NPC1L1, an in vitro system reflecting
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Questions

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  1. How is shipping temperature determined? And how is it related to the product storage temperature?

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    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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  2. How can I determine the shelf life / expiration / retest date of this product?

    1 answer

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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