ABC107

Anti-KIF3A Antibody

from rabbit, purified by affinity chromatography

• Synonym(e): Kinesin-like protein KIF3A, Microtubule plus end-directed kinesin motor 3A
• UNSPSC-Code: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Eigenschaften

• Biologische Quelle: rabbit
• Antikörperform: affinity isolated antibody
• Antikörper-Produkttyp: primary antibodies
• Klon: polyclonal
• Aufgereinigt durch: affinity chromatography
• Speziesreaktivität: human
• Speziesreaktivität (Voraussage durch Homologie): baboon (based on 100% sequence homology), bovine (based on 100% sequence homology), chimpanzee (based on 100% sequence homology)
• Methode(n): immunocytochemistry: suitable
• NCBI-Hinterlegungsnummer: NP_008985
• UniProt-Hinterlegungsnummer: Q9Y496
• Versandbedingung: wet ice
• Posttranslationale Modifikation Target: unmodified
• Angaben zum Gen: human ... KIF3A(11127)

Beschreibung

Allgemeine Beschreibung

Kinesin-like protein KIF3 (KIF3A) is a member of the heteromeric family of kinesins and plays an important role in primary cilia formation. KIF3A functions as a microtubule-based anterograde translocator for membranous organelles and forms a heterotrimeric KIF3 complex with KIF3B or KIF3C and an associated protein, KAP3. Mutations in in KIF3A have been associated with cranial base growth retardation and dysmorphogenesis.

Spezifität

Other homologies: Mouse, Rat, Chicken, Zebrafish, and Frog (92% sequence homology).

Immunogen

KLH-conjugated linear peptide corresponding to human KIF3A.

Anwendung

Research Category
Apoptose & Krebs

Research Sub Category
Apoptose - Weiterführende Produkte

Immunocytochemistry Analysis: A 1:500 dilution from a representative lot detected KIF3A in A431, HeLa, and NIH/3T3 cells.

This Anti-KIF3A Antibody is validated for use in ICC for the detection of KIF3A.

Qualität

Evaluated by Western Blot in SH-SY5Y cell lysate.

Western Blot Analysis: 1 µg/mL of this antibody detected KIF3A in 10 µg of SH-SY5Y cell lysate.

Zielbeschreibung

~80 kDa observed

Physikalische Form

Affinity purified

Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Lagerung und Haltbarkeit

Stable for 1 year at 2-8°C from date of receipt.

Hinweis zur Analyse

Control
SH-SY5Y cell lysate

Sonstige Hinweise

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Sicherheitshinweise

• Lagerklassenschlüssel: 12 - Non Combustible Liquids
• WGK: WGK 1
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable