04-293

Anti-phospho-erbB2 (Thr686) Antibody, clone 7F8

clone 7F8, Upstate^®, from mouse

• Synonym(e): NEU, NGL, HER2, TKR1, HER-2, c-erb B2
• UNSPSC-Code: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Eigenschaften

• Biologische Quelle: mouse
• Qualitätsniveau: 100
• Antikörperform: purified antibody
• Antikörper-Produkttyp: primary antibodies
• Klon: 7F8, monoclonal
• Speziesreaktivität: mouse, human, canine
• Hersteller/Markenname: Upstate^®
• Methode(n): ELISA: suitable; western blot: suitable
• Isotyp: IgG1
• NCBI-Hinterlegungsnummer: NM_001005862.1; NM_004448.2
• UniProt-Hinterlegungsnummer: P04626
• Versandbedingung: wet ice
• Posttranslationale Modifikation Target: phosphorylation (pThr686)
• Angaben zum Gen: human ... ERBB2(2064) ; mouse ... Erbb2(13866)

Beschreibung

Spezifität

Recognizes phosphorylated erbB2 on Threonine 686

Immunogen

KLH-conjugated synthetic peptide encompassing the surrounding amino acids of Thr 686 in human erbB2

Anwendung

Research Category
Zelluläre Signaltransduktion

Research Sub Category
Wachstumsfaktoren & -rezeptoren

Kinasen & Phosphatasen

Anti-phospho-erbB2 (Thr686) Antibody, clone 7F8 is an antibody against phospho-erbB2 (Thr686) for use in ELISA & WB.

Qualität

Routinely evaluated by immunoblot.

Zielbeschreibung

180 kDa

Physikalische Form

Subsequent thiophilic adsorption and size exclusion chromatography

Format: Purified

In 1 mL of PBS containing 0.09% sodium azide, PEG, sucrose and 50% glycerol.

Lagerung und Haltbarkeit

2 years at -20°C from date of shipment. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.

Hinweis zur Analyse

Control
Positive Antigen Control: Catalog #12-302, EGF-stimulated A431 cell lysate. Add 2.5µL of 2-mercaptoethanol/100µL of lysate and boil for 5 minutes to reduce the preparation. Load 20µg of reduced lysate per lane for minigels.

Rechtliche Hinweise

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Sicherheitshinweise

• Lagerklassenschlüssel: 10 - Combustible liquids