a peptide corresponding to amino acids 222-237 of murine Smac/DIABLO.
Linkage
The action of this antibody can be blocked using blocking peptide SBP2411.
Physical form
Solution in phosphate buffered saline containing 0.02% sodium azide
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The Journal of biological chemistry, 295(6), 1623-1636 (2020-01-05)
Permeabilization of the mitochondrial outer membrane is a key step in the intrinsic apoptosis pathway, triggered by the release of mitochondrial intermembrane space proteins into the cytoplasm. The BCL-2-associated X apoptosis regulator (BAX) protein critically contributes to this process by
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