G1763
β-Glutamic acid
≥98% (TLC), suitable for ligand binding assays
Synonym(s):
3-Aminopentanedioic acid
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About This Item
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product name
β-Glutamic acid,
Assay
≥98% (TLC)
form
powder
technique(s)
ligand binding assay: suitable
color
white to off-white
SMILES string
NC(CC(O)=O)CC(O)=O
InChI
1S/C5H9NO4/c6-3(1-4(7)8)2-5(9)10/h3H,1-2,6H2,(H,7,8)(H,9,10)
InChI key
BBJIPMIXTXKYLZ-UHFFFAOYSA-N
Biochem/physiol Actions
β-Glutamic acid (β-Glu) is used as an osmolyte in many archaea. β-Glutamic acid may be used as a substrate to study the specificity and kinetics of archaeal and bacterial glutamine synthetase (GS) enzymes. β-Glutamic acid is used to study primitive mechanisms of polypeptide formation.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Certificates of Analysis (COA)
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Applied and environmental microbiology, 67(10), 4458-4463 (2001-09-26)
The conversion of beta-glutamate to beta-glutamine by archaeal and bacterial glutamine synthetase (GS) enzymes has been examined. The GS from Methanohalophilus portucalensis (which was partially purified) is capable of catalyzing the amidation of this substrate with a rate sevenfold less
Neuropharmacology, 21(6), 549-554 (1982-06-01)
Separate receptors are recognized for the excitation of mammalian neurones by (a) L-glutamic and quisqualic acids and (b) N-methyl-D-aspartic (NMDA), and other amino acids which have conformationally restricted molecules. Several other compounds, both agonists and antagonists, have been examined, and
Applied and environmental microbiology, 56(5), 1504-1508 (1990-05-01)
The unusual compound beta-aminoglutaric acid (beta-glutamate) has been identified by 13C nuclear magnetic resonance spectroscopy in soluble extracts of marine methanogenic bacteria. We examined several methanogen species representing nine genera and found that beta-glutamate occurred in methanococci and two methanogenium
Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life, 28(3), 245-257 (1998-06-05)
We have studied the accumulation of long oligomers of beta-amino acids on the surface of minerals using the 'polymerization on the rocks' protocol. We find that long oligopeptides of beta-glutamic acid which cannot be formed in homogeneous aqueous solution are
Journal of peptide science : an official publication of the European Peptide Society, 7(5), 250-261 (2001-06-29)
A new synthesis of orthogonally protected diaminoglutaric acid containing peptides using the Ugi four component condensation is presented. To demonstrate that this method is useful to replace cystine by diaminoglutaric acid in biologically interesting peptides, we built up two cyclic
Chromatograms
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