Unfortunately, no studies were performed using Diprotin A in blood samples. It is recommended to review the scientific literature. Please see the link below.
https://scholar.google.com/scholar?hl=en&as_sdt=0%2C26&q=What+is+the+final+concentration+of+Diprotin+A++necessary+for+avoiding+GLP-1+degradation+in+blood+samples&btnG=
D3822
Dipeptidyl Peptidase IV Inhibitor I
Synonym(s):
Diprotin A
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About This Item
Empirical Formula (Hill Notation):
C17H31N3O4
Molecular Weight:
341.45
UNSPSC Code:
12352202
NACRES:
NA.77
Pricing and availability is not currently available.
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General description
Dipeptidyl peptidase IV (DPP IV) is a member of the prolyl-specific proteases family. It is a dimeric type II integral membrane glycoprotein that is broadly expressed in the epithelial and nonepithelial tissues. It is majorly expressed in the kidney and the colon.[1]
Application
Dipeptidyl peptidase IV inhibitor I has been used in acute in vivo studies to assess rapid plasma glucagon-like peptide (GLP-1) responses to specified secretory agents in mice.[2]
Biochem/physiol Actions
Dipeptidyl peptidase IV (DPP IV) functions as a modulator of glucagon-like peptide (GLP-1), insulin-stimulating hormones, and glucose-dependent insulinotropic polypeptide (GIP). It is an essential therapeutic target for type 2 diabetes (T2DM).[3] DPP-4 inhibitors are crucial for maintaining glucose homeostasis by prolonging the activity of GLP-1 and GIP. They also enhance glycemic control for a longer period when compared to early oral hypoglycemics.[4] DPP-4 also acts as a binding protein and a ligand of extracellular factors.[5]
Sequence
Ile-Pro-Ile
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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What is the final concentration of Diprotin A (D3822) necessary for avoiding GLP-1 degradation in blood samples?
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