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Y0000612

Dopexamine dihydrochloride

European Pharmacopoeia (EP) Reference Standard

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About This Item

Empirical Formula (Hill Notation):
C22H32N2O2 · 2HCl
CAS Number:
86484-91-5
Molecular Weight:
429.42
UNSPSC Code:
41116107
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

dopexamine

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

[Cl-].[Cl-].N(CCCCCCNCCc2ccccc2)CCc1cc(c(cc1)O)O.[H+].[H+]

InChI

1S/C22H32N2O2.2ClH/c25-21-11-10-20(18-22(21)26)13-17-24-15-7-2-1-6-14-23-16-12-19-8-4-3-5-9-19;;/h3-5,8-11,18,23-26H,1-2,6-7,12-17H2;2*1H

InChI key

VPDULUNRSQWWJB-UHFFFAOYSA-N

Related Categories

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Dopexamine dihydrochloride EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

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B Trabold et al.
Resuscitation, 74(2), 352-356 (2007-03-27)
To elucidate differential functional and phenotypic changes in response to clinically relevant synthetic inotropes plus the generation of oxidative free radicals by polymorphonuclear neutrophils (PMN), and changes in the expression of L-selectin and Mac-1 on the surface of PMN were
D Rapp-Kesek et al.
Acta anaesthesiologica Scandinavica, 51(5), 570-576 (2007-04-14)
After cardiac surgery, patients are at risk of organ dysfunction because of decreased perfusion. Different measures have been used to increase the splanchnic blood flow. We compared the effects of enteral nutrition and dopexamine on the cardiac output, splanchnic blood
Myron M Kwapisz et al.
Paediatric anaesthesia, 19(9), 862-871 (2009-08-05)
After surgical repair of congenital heart disease, inotropic support is sometimes necessary to wean from cardiopulmonary bypass. In pediatric cardiac surgery, dobutamine and dopamine are often used as inotropic support. Dopexamine is a synthetic catecholamine, which has positive inotropic and
Georgios I Tagarakis et al.
Recent patents on cardiovascular drug discovery, 5(1), 66-68 (2009-11-26)
A great variety of inotropic agents with different effects on peripheral vascular resistance have been employed in the endeavor to treat heart failure after cardiac surgery. Epinephrine, norepinephrine, dopamine and dobutamine belong to the first-line, widely used drugs recruited to
S Gopal et al.
Anaesthesia, 64(6), 589-594 (2009-05-21)
The objective of the study was to determine whether dopexamine alters in-hospital mortality. The following databases were searched, Embase (1974-July 2007), Medline (1950-July 2007), CINAHL, PubMed and Cochrane Clinical Register of Controlled Trials (CENTRAL). Two reviewers independently checked the quality
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