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Supelco

Prochloraz

PESTANAL®, analytical standard

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About This Item

Empirical Formula (Hill Notation):
C15H16Cl3N3O2
CAS Number:
67747-09-5
Molecular Weight:
376.67
Beilstein:
8155344
EC Number:
266-994-5
MDL number:
MFCD00078735
UNSPSC Code:
41116107
PubChem Substance ID:
329756845
NACRES:
NA.24

grade

analytical standard

Quality Level

100

product line

PESTANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

agriculture
environmental

format

neat

SMILES string

CCCN(CCOc1c(Cl)cc(Cl)cc1Cl)C(=O)n2ccnc2

InChI

1S/C15H16Cl3N3O2/c1-2-4-20(15(22)21-5-3-19-10-21)6-7-23-14-12(17)8-11(16)9-13(14)18/h3,5,8-10H,2,4,6-7H2,1H3

InChI key

TVLSRXXIMLFWEO-UHFFFAOYSA-N

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General description

Prochloraz belongs to the imidazole class of fungicides, with protective and curative action, found to be effective against different fungi affecting cereal crops, turf, citrus and tropical fruit, field legumes and beet. Its mode of action involves the inhibition of ergosterol biosynthesis.

Application

Prochloraz may be used as an analytical reference standard for the quantification of the analyte in agricultural commodities using different chromatography techniques.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Legal Information

PESTANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictograms

Exclamation markEnvironment
GHS07,GHS09

Signal Word

Warning

Hazard Statements

H302 - H410

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
BCCG1684
BCCB7755
BCBW4694
SZBD077XV
SZBA112XV

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Simplified determination of combined residues of prochloraz and its metabolites in vegetable, fruit and wheat samples by gas chromatography
Paoli D.M, et al.
Journal of Chromatography A, 765(1), 127-131 (1997)
Nigel C Noriega et al.
Biology of reproduction, 72(6), 1324-1335 (2005-01-28)
Prochloraz (PZ) is an imidazole fungicide that displays multiple endocrine activities. It inhibits steroid synthesis via P450 modulation and acts as an androgen receptor (AR) antagonist, but its effects on male sexual differentiation have not been described. The purpose of
Determination of fungicide residues in fruits and vegetables by liquid chromatography-atmospheric pressure chemical ionization mass spectrometry
Blasco C, et al.
Journal of Chromatography A, 947(2), 227-235 (2002)
The Pesticide Encyclopedia (2014)
Frederik Knud Nielsen et al.
Toxicology in vitro : an international journal published in association with BIBRA, 26(2), 343-350 (2011-12-27)
The effects of three model endocrine disruptors, prochloraz, ketoconazole and genistein on steroidogenesis were tested in the adrenocortical H295R cell line to demonstrate that a broader mechanistic understanding can be achieved in one assay by applying chemical analysis to the
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