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06679

Sigma-Aldrich

Methoxypolyethylene glycol amine

5,000, extent of labeling: ≥0.17 mmol/g NH2 loading

Synonym(s):

O-(2-Aminoethyl)-O′-methylpolyethylene glycol, Aminopolyethylene glycol monomethyl ether, Methoxypolyoxyethylene amine

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About This Item

Linear Formula:
H2NCH2CH2(OCH2CH2)nOCH3
CAS Number:
MDL number:
UNSPSC Code:
12162002
PubChem Substance ID:
NACRES:
NA.22
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Quality Level

extent of labeling

≥0.17 mmol/g NH2 loading

InChI

1S/C3H9NO/c1-5-3-2-4/h2-4H2,1H3

InChI key

ASUDFOJKTJLAIK-UHFFFAOYSA-N

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Application

Methoxypolyethylene glycol amine is generally used for the chemical modification of biologically active compounds and therapeutic agents.[1] It has been used to increase the aqueous solubility of long-wavelength voltage-sensitive dyes[2] and to prepare the PEG-coated fluorescent beads in studying large-scale rotational cytoplasmic flow.[3]

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

>230.0 °F

Flash Point(C)

> 110 °C

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Spatial confinement of active microtubule networks induces large-scale rotational cytoplasmic flow
Suzuki K, et al.
Test, 114(11), 2922-2927 (2017)
Tools for Drug Discovery
Aldrich Chemfiles, 5(12), 19-20 (2005)
Enhanced aqueous solubility of long wavelength voltage-sensitive dyes by covalent attachment of polyethylene glycol
Patrick MJ, et al.
Organic & Biomolecular Chemistry, 5(20), 3347-3353 (2007)

Articles

Biofouling control essential for device performance and safety; minimize accumulation of biomolecules and bioorganisms.

Biofouling control essential for device performance and safety; minimize accumulation of biomolecules and bioorganisms.

Biofouling control essential for device performance and safety; minimize accumulation of biomolecules and bioorganisms.

Biofouling control essential for device performance and safety; minimize accumulation of biomolecules and bioorganisms.

Questions

  1. Can you provide the number of repeating units and structure of this compound.

    1 answer
    1. The average molecular weight is 5,000 daltons, so that would mean there are 111.80 O(CH2)2 units in each chain, on average. The math on this is 5,000 minus 75.11 (to account for the end groups), and then dividing by 44.05 (the mass of one O(CH2)2 unit). This is an average, of course, and the chains will vary in length.

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