Skip to Content
Merck
All Photos(1)

Documents

2011

Millipore

Bilirubin

solid, bile pigment, Calbiochem®

Synonym(s):

Bilirubin

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Empirical Formula (Hill Notation):
C33H36N4O6
CAS Number:
635-65-4
Molecular Weight:
584.66
MDL number:
MFCD00005499
UNSPSC Code:
12352200
NACRES:
NA.77

product name

Bilirubin, Principal pigment of bile and one of the major end products of hemoglobin decomposition.

Quality Level

100

form

solid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze
protect from light

color

red-brown

solubility

chloroform: 1 mg/mL
alkaline solution: soluble

shipped in

ambient

storage temp.

10-30°C

InChI

1S/C33H36N4O6/c1-7-20-19(6)32(42)37-27(20)14-25-18(5)23(10-12-31(40)41)29(35-25)15-28-22(9-11-30(38)39)17(4)24(34-28)13-26-16(3)21(8-2)33(43)36-26/h7-8,13-14,34-35H,1-2,9-12,15H2,3-6H3,(H,36,43)(H,37,42)(H,38,39)(H,40,41)/b26-13-,27-14-

InChI key

BPYKTIZUTYGOLE-IFADSCNNSA-N

General description

Bilirubin is an orange-yellow bile pigment and one of the major end products of hemoglobin decomposition. It contains conjugated double bonds and reactive hydrogen atoms. In adults, the upper limit of the normal range of bilirubin is >1mg/dL. Serum levels of bilirubin in healthy newborns are less than 15 mg/dl. This product corresponds to the unconjugated form.

Biochem/physiol Actions

Bilirubin is reported to cross the blood-brain barrier and exert significant antioxidant effects in the brain. This pigment aids in coloration in the various forms of jaundice. Bilirubin levels act as biomarkers in liver and blood disorders. Unconjugated form of bilirubin at lower levels serves as a physiological antioxidant. However, increased concentration of bilirubin is toxic and leads to neonatal hyperbilirubinemia in neonates.

Reconstitution

Unstable in basic solutions; reconstitute just prior to use.

Other Notes

Extinction coefficient (454 nm, CHCl3):59,100-62,300 M-1cm-1.
Cell permeable: no
Reversible: no
Product does not compete with ATP.
Primary Target

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

What's in a name? Physiologic and pathologic jaundice: the conundrum of defining normal bilirubin levels in the newborn.
M Jeffrey Maisels
Pediatrics, 118(2), 805-807 (2006-08-03)
Zeng Hong et al.
ACS omega, 5(46), 29903-29912 (2020-12-01)
The reaction of magnesium or zinc amides with alkyl or benzyl halides is an attractive approach to make C-N bonds, especially for electron-poor organic halides. The magnesium-promoted preparation of hindered non-nucleophilic amine (N,N-diisopropylethylamine) from ethyl chloride and zinc diisopropylamide has
Elisabeth Lobner et al.
Frontiers in bioengineering and biotechnology, 8, 49-49 (2020-03-03)
The transmembrane protein CD19 is exclusively expressed on normal and malignant B cells and therefore constitutes the target of approved CAR-T cell-based cancer immunotherapies. Current efforts to assess CAR-T cell functionality in a quantitative fashion both in vitro and in
E Jiménez et al.
Environmental toxicology and pharmacology, 80, 103464-103464 (2020-08-05)
The identification of substances that prevent or minimize the detrimental effects of ionizing radiation is an essential undertaking. The aim of this paper was to evaluate and compare the radioprotective potential of chlorophyllin, protoporphyrin and bilirubin, with amifostine®, an US
Jürgen Reingruber et al.
The Journal of physiology, 598(17), 3747-3763 (2020-06-20)
Most vertebrate eyes have rods for dim-light vision and cones for brighter light and higher temporal sensitivity. Rods evolved from cone-like precursors through expression of different transduction genes or the same genes at different expression levels, but we do not
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service