07-585
Anti-dimethyl-Histone H3 (Arg2) Antibody
serum, Upstate®
Synonym(s):
H3R2me2, Histone H3 (di methyl R2)
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About This Item
UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Recommended Products
biological source
rabbit
Quality Level
antibody form
serum
antibody product type
primary antibodies
clone
polyclonal
species reactivity
human, chicken
manufacturer/tradename
Upstate®
technique(s)
inhibition assay: suitable (peptide)
western blot: suitable
isotype
IgG
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
dimethylation (Arg2)
Gene Information
human ... H3F3B(3021)
Specificity
Broad species cross-reactivity expected
dimethyl-arginine at residue 2 of histone H3
Immunogen
peptide containing the sequence AdimRT, corresponding to dimethyl-arginine 2 of human histone H3
Application
Anti-dimethyl-Histone H3 (Arg2) Antibody is a Rabbit Polyclonal Antibody for detection of dimethyl-Histone H3 (Arg2) also known as H3R2me2, Histone H3 (di methyl R2) & has been validated in WB, PIA.
Research Category
Epigenetics & Nuclear Function
Epigenetics & Nuclear Function
Research Sub Category
Histones
Histones
Quality
routinely evaluated by immunoblot on acid-extracted proteins from chicken erythrocyte cells (Catalog # 13-107)
Target description
Mr 17kDa
Physical form
Serum
rabbit antiserum containing 0.05% sodium azide, before the addition of glycerol to 30%
Storage and Stability
2 years at -20°C
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
12 - Non Combustible Liquids
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Sinja Rakow et al.
Methods (San Diego, Calif.), 175, 53-65 (2019-09-23)
Among the widespread and increasing number of identified post-translational modifications (PTMs), arginine methylation is catalyzed by the protein arginine methyltransferases (PRMTs) and regulates fundamental processes in cells, such as gene regulation, RNA processing, translation, and signal transduction. As epigenetic regulators
PELP1 oncogenic functions involve alternative splicing via PRMT6.
Mann, M; Zou, Y; Chen, Y; Brann, D; Vadlamudi, R
Molecular Oncology null
Jihee Hong et al.
Journal of ginseng research, 46(3), 481-488 (2022-05-24)
Although the tumor-suppressive effects of ginsenosides in cell cycle have been well established, their pharmacological properties in mitosis have not been clarified yet. The chromosomal instability resulting from dysregulated mitotic processes is usually increased in cancer. In this study, we
Claudia Stein et al.
Nucleic acids research, 40(19), 9522-9533 (2012-08-21)
The protein arginine methyltransferase 6 (PRMT6) is a coregulator of gene expression and executes its repressing as well as activating function by asymmetric dimethylation of histone H3 at R2 (H3 R2me2a). Given that elevated expression levels of PRMT6 have been
Haolin Liu et al.
Proceedings of the National Academy of Sciences of the United States of America, 114(37), E7717-E7726 (2017-08-30)
Two of the unsolved, important questions about epigenetics are: do histone arginine demethylases exist, and is the removal of histone tails by proteolysis a major epigenetic modification process? Here, we report that two orphan Jumonji C domain (JmjC)-containing proteins, JMJD5
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