216410
Amberlyst® A21 Ion Exchange Resin
free base, 16-50 mesh
Synonym(s):
weak anion exhange resin (DMA)
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About This Item
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product name
Amberlyst® A21 free base, free base
vapor density
<1 (vs air)
Quality Level
vapor pressure
17 mmHg ( 20 °C)
form
beads
autoignition temp.
800 °F
moisture
56-62%
technique(s)
LPLC: suitable
matrix
styrene divinylbenzene (macroporous)
matrix active group
dimethylamino
particle size
22-30 mesh
490-690 μm
capacity
1.3 meq/mL by wetted bed volume
separation technique
anion exchange
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General description
Amberlyst A21 is a neutral ion-exchange resin and a solid base which catalyses three-component reaction of aldehyde and malononitrile with various active methylene compounds to synthesize a range of pyran annulated heterocycles. Use of the solid base is to generate a highly green protocol by eliminating chromatographic purification involving hazardous organic solvents, and for easy recovery and reusability of the catalyst. Amberlyst A21 is used as a fluid bed resin. Fluid bed reactor allows gel-type beads, of polymer-supported (PS) organic reactions, to be used in a flow system. The Michael reaction between methyl 1-oxoindan-2-carboxylate and methyl vinyl ketone in toluene can be attained through a fluid bed of Amberlyst A21 at 50°C.
Application
Amberlyst® A21 free base was used in catalyst preparation.
Features and Benefits
Weakly basic, macroreticular resin with alkyl amine functionality.
Legal Information
Amberlyst is a registered trademark of The Dow Chemical Company or an affiliated company of Dow
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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Organic & biomolecular chemistry, 4(3), 493-497 (2006-02-01)
The Michael reaction between methyl 1-oxoindan-2-carboxylate and methyl vinyl ketone was achieved successfully by pumping solutions of the reactants in toluene through a fluid bed of Amberlyst A21 at 50 degrees C. The use of a fluid bed reactor is
Amberlyst A21: A reusable solid catalyst for green synthesis of pyran annulated heterocycles at room temperature.
Comptes Rendus Chimie, 16, 419-426 (2013)
Transformation of Biomass Products into Fine Chemicals Catalyzed by Solid Lewis-and Br?nsted-acids.
Topics in Catalysis, 52, 1182-1189 (2009)
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