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Sigma-Aldrich

Triethylenetetramine tetrahydrochloride

97%

Synonym(s):

Cuprior, Trientine tetrahydrochloride

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About This Item

Linear Formula:
NH2CH2CH2(NHCH2CH2)2NH2 · 4HCl
CAS Number:
4961-40-4
Molecular Weight:
292.08
EC Number:
225-604-3
MDL number:
MFCD00012890
UNSPSC Code:
12352100
PubChem Substance ID:
24849963
NACRES:
NA.22
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Assay

97%

mp

269-270 °C (lit.)

functional group

amine

SMILES string

Cl.Cl.Cl.Cl.NCCNCCNCCN

InChI

1S/C6H18N4.4ClH/c7-1-3-9-5-6-10-4-2-8;;;;/h9-10H,1-8H2;4*1H

InChI key

OKHMDSCYUWAQPT-UHFFFAOYSA-N

Related Categories

General description

Triethylenetetramine tetrahydrochloride is a copper-chelating agent[1]

Application

Triethylenetetramine tetrahydrochloride was used as primary amine displacer in affinity chromatography[2].

Biochem/physiol Actions

Triethylenetetramine tetrahydrochloride induces apoptosis of acinar cells of the pancreas in male Fischer 344 rats[1].

Pictograms

Health hazardExclamation mark
GHS08,GHS07

Signal Word

Warning

Hazard Statements

H315,H319,H335,H351

Hazard Classifications

Carc. 2 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
0000373865
0000331781
0000331782
0000373865
0000359430

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Structural characteristics of low-molecular-mass displacers for cation-exchange chromatography: II. Role of the stationary phase.
Shukla AA, et al.
Journal of Chromatography A, 872(2), 295-310 (1998)
S Kishimoto et al.
Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie, 45(8), 489-495 (1994-04-01)
Male Fischer 344 rats weighing 80-90 g were fed on a copper-depleted diet supplemented with 0.6% triethylenetetramine tetrahydrochloride (a copper chelator), and the death of pancreatic acinar cells of these rats was investigated morphologically and biochemically. The weight of the
Concetta R Capo et al.
Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS), 44, 225-232 (2017-10-03)
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