T8657

Trichloroacetic acid

suitable for electrophoresis, suitable for fixing solution (for IEF and PAGE gels), ≥99%

• Synonyme(s) : TCA
• Formule linéaire : Cl₃CCOOH
• Numéro CAS: 76-03-9
• Poids moléculaire : 163.39
• UNSPSC Code: 41105319
• NACRES: NB.22
• PubChem Substance ID: 24900550
• EC Number: 200-927-2
• Beilstein/REAXYS Number: 970119
• MDL number: MFCD00004177
• Assay: ≥99%
• Form: powder or flakes (or crystals)
• Grade: electrophoresis grade

Propriétés

• grade: electrophoresis grade
• Quality Segment: 200
• vapor density: <1 (vs air)
• vapor pressure: 1 mmHg ( 51 °C)
• assay: ≥99%
• form: powder or flakes (or crystals)
• technique(s): electrophoresis: suitable
• turbidity: ≤3 NTU (1 g/ml)
• refractive index: n20/D 1.62 (lit.)
• bp: 196 °C (lit.)
• mp: 54-58 °C (lit.)
• solubility: water: 1 g/mL, clear, colorless
• density: 1.62 g/mL at 25 °C (lit.)
• anion traces: chloride (Cl^-): ≤0.001%, nitrate (NO₃^-): ≤0.002%, phosphate (PO₄^3-): ≤5 ppm, sulfate (SO₄^2-): ≤0.02%
• cation traces: Fe: ≤0.0005%, heavy metals (as Pb): ≤0.002%
• suitability: suitable for fixing solution (for IEF and PAGE gels)
• application(s): cell analysis
• storage temp.: 2-8°C
• SMILES string: OC(=O)C(Cl)(Cl)Cl
• InChI: 1S/C2HCl3O2/c3-2(4,5)1(6)7/h(H,6,7)
• InChI key: YNJBWRMUSHSURL-UHFFFAOYSA-N

Description

General description

Trichloroacetic acid (TCA) is produced during the chlorination of water comprising natural organic material. It is a novel reagent used in clinical laboratories for deproteinization of body fluids. In addition, TCA is also used in the treatment of genital warts and acne scars.

Application

Traditionally used to precipitate protein. Has been used to determine protein concentration by quantitative precipitation. Used as decalcifier and fixative in microscopy.

Trichloroacetic acid has been used:

• for hydrolysis of DNA isolated from the cell
• for precipitation of glutathione isolated from seminal plasma
• as a fixative in microscopy

Informations sur la sécurité

• pictograms: GHS05,GHS09
• signalword: Danger
• hcodes: H314,H410
• pcodes: P260 - P273 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Hazard Classifications: Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Skin Corr. 1A
• wgk: WGK 2
• flash_point_f: >235.4 °F - closed cup
• flash_point_c: > 113 °C - closed cup
• ppe: Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
• Classe de stockage: 8A - Combustible corrosive hazardous materials