T6271

Tylosin tartrate

powder, suitable for cell culture, BioReagent

• UNSPSC Code: 12352207
• PubChem Substance ID: 24900364
• NACRES: NA.76
• MDL number: MFCD07783824

Propriétés

• Nom du produit: Tylosin tartrate, powder, BioReagent, suitable for cell culture
• product line: BioReagent
• Quality Segment: 200
• form: powder
• potency: ≥800 units/mg tylosin
• storage condition: (Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place.)
• technique(s): cell culture | mammalian: suitable
• color: off-white to yellow
• solubility: H₂O: ≤50 mg/mL
• antibiotic activity spectrum: Gram-positive bacteria, mycoplasma
• mode of action: protein synthesis | interferes
• storage temp.: 2-8°C
• SMILES string: O[C@H]([C@@H](O)C(O)=O)C(O)=O.CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O[C@H]3C[C@@](C)(O)[C@@H](O)[C@H](C)O3)[C@@H]([C@H]2O)N(C)C)[C@@H](CC=O)C[C@@H](C)C(=O)\C=C\C(C)=C\[C@@H]1CO[C@@H]4O[C@H](C)[C@@H](O)[C@@H](OC)[C@H]4OC
• InChI: 1S/C46H77NO17.C4H6O6/c1-13-33-30(22-58-45-42(57-12)41(56-11)37(52)26(5)60-45)18-23(2)14-15-31(49)24(3)19-29(16-17-48)39(25(4)32(50)20-34(51)62-33)64-44-38(53)36(47(9)10)40(27(6)61-44)63-35-21-46(8,55)43(54)28(7)59-35;5-1(3(7)8)2(6)4(9)10/h14-15,17-18,24-30,32-33,35-45,50,52-55H,13,16,19-22H2,1-12H3;1-2,5-6H,(H,7,8)(H,9,10)/b15-14+,23-18+;/t24-,25+,26-,27-,28+,29+,30-,32-,33-,35+,36-,37-,38-,39-,40-,41-,42-,43+,44+,45-,46-;1-,2-/m11/s1
• InChI key: ICVKYYINQHWDLM-KBEWXLTPSA-N

Description

General description

Chemical structure: macrolide

Application

Tylosin is a mcrolide antibiotic commonly used in veterinary medicine. It has been used to study protein synthesis at the 50S ribosome, implant site abscess prevention in cattle, disposition kinetics and Mycoplasma gallisepticumand Mycoplasma meleagridis infections. It is recommended for use in cell culture applications at 8 mg/L.

Biochem/physiol Actions

Mode of Action: Tylosin Tartrate inhibits bacterial protein synthesis by binding to the 50S (L27 protein) ribosome.

Antimicrobial Spectrum: This product acts against gram-positive bacteria and mycoplasma.

Other Notes

Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place.

This product is a mixture of tylosin A, B, C, and D tartrates.

Disclaimer

Stock solutions should be filter sterilized and stored at 2-8°C. These solutions are stable at 37°C for 3 days.

Informations sur la sécurité

• Pictogrammes: GHS08
• Mot-clé: Danger
• Codes de danger: H317,H334
• Mentions de précaution: P280 - P302 + P352
• Hazard Classifications: Resp. Sens. 1 - Skin Sens. 1
• Classe de stockage: 11 - Combustible Solids
• Que se passe-t-il ?: WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• EPI (équipement de protection individuelle): dust mask type N95 (US), Eyeshields, Faceshields, Gloves