T1892

Thioflavine S

Practical grade, powder

• Synonyme(s) : Direct Yellow 7
• Numéro CAS: 1326-12-1
• NACRES: NA.47
• UNSPSC Code: 12171500
• EC Number: 215-418-0
• MDL number: MFCD00071453
• Colour Index Number: 49010

Propriétés

• Nom du produit: Thioflavine S, practical grade
• grade: practical grade
• Quality Segment: 200
• form: powder
• technique(s): microbe id | staining: suitable
• color: light beige to dark beige, to Dark Brown
• solubility: ethanol: water (1:1): 1 mg/mL
• λmax: 360-380
• application(s): diagnostic assay manufacturing; hematology; histology
• storage temp.: room temp
• SMILES string: S1c2c(ccc(c2)C)N(C1=C3C=CC(=[N+](C)C)C=C3)C.[Cl-]
• InChI: 1S/C17H19N2S.ClH/c1-12-5-10-15-16(11-12)20-17(19(15)4)13-6-8-14(9-7-13)18(2)3;/h5-11H,1-4H3;1H/q+1;/p-1
• InChI key: JADVWWSKYZXRGX-UHFFFAOYSA-M

Description

General description

Thioflavine S aids in staining and visualizing β-amyloid plaques in Alzheimer′s disease. Thioflavin S binds to fibrillar β-amyloid plaques, and does not diffuse in the plaques. Thioflavin-S staining aids in visualizing smaller plaques throughout the neocortex, hippocampus and thalamic region.

Application

Thioflavine S has been used to stain and visualize β-amyloid structures in the tissue sections.

Other Notes

2024 CiteAb Award Winner for Supplier Succeeding in Parkinson′s Research

Informations sur la sécurité

• pictograms: GHS07
• signalword: Warning
• hcodes: H315,H319,H335
• pcodes: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Classe de stockage: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves