SML1118

Hepcidin-25 (human) trifluoroacetate salt

≥95% (HPLC), iron homeostasis regulator, powder

• Synonyme(s) : DTHFPICIFCCGCCHRSKCGMCCKT trifluoroacetate salt, H-Asp-Thr-His-Phe-Pro-Ile-Cys-Ile-Phe-Cys-Cys-Gly-Cys-Cys-His-Arg-Ser-Lys-Cys-Gly-Met-Cys-Cys-Lys-Thr-OH trifluoroacetate salt, Hepc25 (human), LEAP-1 (Liver-Expressed Antimicrobial Peptide) (human) trifluoroacetate salt, PLTR (Putative Liver Tumor Regressor ) (human)
• Formule empirique (notation de Hill) : C₁₁₃H₁₇₀N₃₄O₃₁S₉ · xC₂HF₃O₂
• Numéro CAS: 342809-17-0
• Poids moléculaire : 2789.35 (free base basis)
• UNSPSC Code: 12352200
• NACRES: NA.77
• Assay: ≥95% (HPLC)
• Form: powder

Propriétés

• Nom du produit: Hepcidin-25 (human) trifluoroacetate salt, ≥95% (HPLC)
• assay: ≥95% (HPLC)
• form: powder
• color: white to off-white
• shipped in: wet ice
• storage temp.: −20°C

Description

Biochem/physiol Actions

Hepcidin is the master regulator of iron homeostasis with anti-inflammatory and antimicrobial activity.

Hepcidin is the master regulator of iron homeostasis. Hepcidin is found in liver, but also widely distributed in brain, where it may play a role in preventing iron-related neurodegeneration. Hepcidin has anti-inflammatory and antimicrobial activity.

Hepcidin-25 is the major isoform of hepcidin. hepcidin‐25 with reticulocyte hemoglobin content (CHr) in the hepcidin‐25 plot helps to differentiate DA can be differentiated iron‐deficient anemia (IDA) from the anemia of chronic disease (ACD) and the combined state of ACD/IDA. Mutation in the hepcidin gene is associated with the development of severe juvenile hemochromatosis.

Informations sur la sécurité

• Classe de stockage: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable