SML0956

Dexmedetomidine hydrochloride

≥98% (HPLC)

• Synonyme(s) : (+)-Medetomidine hydrochloride, (S)-Medetomidine hydrochloride, 4-[(S)-α,2,3-Trimethylbenzyl]imidazole monohydrochloride, 5-[(1S)-1-(2,3-Dimethylphenyl)ethyl]-1H-imidazole hydrochloride
• Formule empirique (notation de Hill): C₁₃H₁₆N₂ · HCl
• Numéro CAS: 145108-58-3
• Poids moléculaire : 236.74
• Code UNSPSC : 12352200
• Nomenclature NACRES : NA.77

Propriétés

• Pureté: ≥98% (HPLC)
• Forme: powder
• Activité optique: [α]/D +48 to +58°, c = 1 in H₂O
• Conditions de stockage: desiccated
• Couleur: white to beige
• Solubilité: H₂O: 20 mg/mL, clear
• Température de stockage: 2-8°C
• InChI: 1S/C13H16N2.ClH/c1-9-5-4-6-12(10(9)2)11(3)13-7-14-8-15-13;/h4-8,11H,1-3H3,(H,14,15);1H/t11-;/m0./s1
• Clé InChI: VPNGEIHDPSLNMU-MERQFXBCSA-N

Description

Application

Dexmedetomidine hydrochloride has been used to study its effects on primary neonatal rat cardiomyocytes under hypoxic/reoxygenation conditions. It has also been used to study the effects of dexmedetomidine pretreatment on lipopolysaccharide-induced acute lung injury in mice.

Actions biochimiques/physiologiques

Dexmedetomidine hydrochloride is a highly potent and selective α2-adrenergic agonist with analgesic and sedative properties, the (+)-isomer of medetomidine. Dexmedetomidine hydrochloride is used clinically as an anesthetic agent to reduce anxiety and tension and promote relaxation and sedation without causing respiratory depression.

Caractéristiques et avantages

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Autres remarques

2024 CiteAb Award Winner for Supplier Succeeding in Parkinson′s Research

Informations sur la sécurité

• Pictogrammes: GHS07,GHS09
• Mention d'avertissement: Warning
• Mentions de danger: H302,H336,H411
• Conseils de prudence: P261 - P264 - P271 - P273 - P301 + P312 - P304 + P340 + P312
• Classification des risques: Acute Tox. 4 Oral - Aquatic Chronic 2 - STOT SE 3
• Organes cibles: Central nervous system
• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable