SML0289

Bromfenac sodium

≥98% (HPLC), COX1 and COX2 inhibitor, powder

• Synonyme(s) : 2-Amino-3-(4-bromobenzoyl)benzeneacetic acid sodium salt
• Formule empirique (notation de Hill) : C₁₅H₁₁BrNNaO₃
• Numéro CAS: 91714-93-1
• Poids moléculaire : 356.15
• UNSPSC Code: 12352200
• PubChem Substance ID: 329825297
• NACRES: NA.77
• MDL number: MFCD03701673
• Assay: ≥98% (HPLC)
• Form: powder
• Storage condition: desiccated

Propriétés

• Nom du produit: Bromfenac sodium, ≥98% (HPLC)
• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: powder
• storage condition: desiccated
• color: faintly yellow to dark yellow
• solubility: H₂O: ≥5 mg/mL
• storage temp.: 2-8°C
• SMILES string: [Na+].Nc1c(CC([O-])=O)cccc1C(=O)c2ccc(Br)cc2
• InChI: 1S/C15H12BrNO3.Na/c16-11-6-4-9(5-7-11)15(20)12-3-1-2-10(14(12)17)8-13(18)19;/h1-7H,8,17H2,(H,18,19);/q;+1/p-1
• InChI key: HZFGMQJYAFHESD-UHFFFAOYSA-M
• Gene Information: human ... PTGS1(5742), PTGS2(5743)

Description

Application

Bromfenac sodium has been used:

• to study its ability to bind to melanin
• in the synthesis of bromfenac indolinone standard
• to analyze its permeability in porcine conjunctiva

Biochem/physiol Actions

Bromfenac is a nonsteroidal anti inflammatory drug (NSAID) that inhibits both COX1 and COX2. It is used as an opthalmic analgesic.

Bromfenac is a nonsteroidal anti inflammatory drug (NSAID); COX1 and COX2 inhibitor; opthalmic analgesic.

Bromfenac exhibits antipyretic and prostaglandin synthetase inhibiting properties. It has therapeutic properties against the reduction of ocular pain and inflammation in postoperative cataract patients. Bromfenac acts as an effective agent against allergic conjunctivitis. It has the potential to treat acute muscle pain, osteoarthritis, and rheumatoid arthritis.

Informations sur la sécurité

• Pictogrammes: GHS06
• Mot-clé: Danger
• Codes de danger: H301
• Mentions de précaution: P264 - P270 - P301 + P310 - P405 - P501
• Hazard Classifications: Acute Tox. 3 Oral
• Classe de stockage: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• Que se passe-t-il ?: WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable