SMB00577
Diallyl trisulfide
≥97% (HPLC)
Synonyme(s) :
Allyl trisulfide, Di-2-propenyl trisulfide
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A propos de cet article
Formule empirique (notation de Hill) :
C6H10S3
Numéro CAS:
Poids moléculaire :
178.34
NACRES:
NA.25
PubChem Substance ID:
UNSPSC Code:
12352200
EC Number:
218-107-8
MDL number:
Service technique
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Allium sativum L.
Quality Segment
assay
≥97% (HPLC)
form
liquid
application(s)
metabolomics
vitamins, nutraceuticals, and natural products
storage temp.
−20°C
SMILES string
C=CCSSSCC=C
InChI
1S/C6H10S3/c1-3-5-7-9-8-6-4-2/h3-4H,1-2,5-6H2
InChI key
UBAXRAHSPKWNCX-UHFFFAOYSA-N
General description
Diallyl trisulfide (DATS) is one of the stable naturally occurring bioactive polysulfide compounds found in Allium vegetables, especially in garlic.
Application
Diallyl trisulfide (DATS) has been used as an exogenous hydrogen sulfide (H2S)donor to study the effects on proliferation, apoptosis, and autophagy of human urothelial carcinoma (UC) cells in vitro.
Biochem/physiol Actions
Diallyl trisulfide elicits cardioprotective and anti-metabolic syndrome (MetS) effects against ex vivo induced myocardial ischemia/reperfusion (I/R) injury in MetS rats (male Wistar albino). It is a potent anti-cancer agent and acts by modulating different cancer-related pathways, inducing cell cycle arrest, apoptosis, metastasis, and angiogenesis in in vitro studies. DATS is also an effective therapeutic agent against multidrug resistance in triple-negative breast cancer (TNBC). DATS and its nanoemulsions display high antifungal activity against wood-rotting fungi such as T. hirsuta and L. sulphureus. It also provides protection against brain damage induced by ischemia/reperfusion (I/R) by activating nuclear factor erythroid 2-related factor 2 (Nrf2) in rat brains.
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Mot-clé
Danger
Codes de danger
Hazard Classifications
Acute Tox. 3 Oral
Classe de stockage
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
Point d'éclair (°F)
Not applicable
Point d'éclair (°C)
Not applicable
Mentions de précaution
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