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Merck

S9991

Recombinant SARS-CoV-2 nucleocapsid protein

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A propos de cet article

NACRES:
NA.26
UNSPSC Code:
12352202
Technique(s):
ELISA: suitable, lateral flow assay: suitable
Species reactivity:
-
Application:
ELISA, lateral flow assay
Citations:
-
Service technique
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form

frozen liquid

Quality Segment

storage condition

avoid repeated freeze/thaw cycles

technique(s)

ELISA: suitable, lateral flow assay: suitable

storage temp.

−70°C

General description

This Nucleoprotein (nucleocapsid protein) of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is expressed in insect cells. The Nucleocapsid protein is not important for determination of neutralizing IgG antibodies. However, the recombinant SARS-CoV-2 Nucleocapsid Protein, S9991 antigen in combination with monoclonal antibodies directed against neutralizing epitopes such as the ACE2 binding domain could be used in a competitive setup for determining neutralizing antibodies. The nucleocapsid protein is quite conserved. Using nucleocapsid protein for acute / early antibodies such as IgA/ IgM should make it possible to detect antibodies directed against the variants of concern in a satisfactory way at an early stage of illness.
For IgM detection, a mixture of nucleocapsid and spike proteins is recommended.


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12 - Non Combustible Liquids

wgk

WGK 1



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