Accéder au contenu
Merck
Toutes les photos(2)

Documents

S4521

Sigma-Aldrich

Saponin from Quillaja sp.

Sapogenin content 20-35 %

Se connecterpour consulter vos tarifs contractuels et ceux de votre entreprise/organisme
Toutes les photos(2)

About This Item

Numéro CAS:
8047-15-2
Numéro CE :
232-462-6
Numéro MDL:
MFCD00081981
Code UNSPSC :
12161902
Nomenclature NACRES :
NA.32

Description

non-ionic

Niveau de qualité

300

Composition

Sapogenin content, 20-35%

Technique(s)

HPLC: suitable
protein quantification: suitable

Cendres sulfatées

≤10%

Description générale

Saponins are steroid or triterpenoid glycosides. They are biosurfactants that have several uses in the food and cosmetic industry.

Application

Saponin from Quillaja bark has been used:
  • to stain fertilized oocytes
  • in the analysis of intracellular cytokine production
  • to permeabilize dendritic cells

Actions biochimiques/physiologiques

Saponins solubilize the low density lipoprotein (LDL) fraction of cholesterol in micelles, thus lowering their concentration. Saponin from Quillaja bark is used as a flavoring agent in food and beverages. This saponin has been shown to enhance immune-cell proliferation in vitro.
Potent hemolytic when injected i.v.; surfactant that enhances penetration of proteins and other macromolecules through cell membranes; it also has been used as an adjuvant for vaccines.

Notes préparatoires

Purified to remove low molecular weight contaminants 

Pictogrammes

Exclamation mark
GHS07

Mention d'avertissement

Warning

Mentions de danger

H319,H335

Classification des risques

Eye Irrit. 2 - STOT SE 3

Organes cibles

Respiratory system

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 2

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

dust mask type N95 (US), Eyeshields, Gloves

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

Déjà en possession de ce produit ?

Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

Consulter la Bibliothèque de documents

Les clients ont également consulté

Slide 1 of 6

1 of 6

Soyasapogenol B ≥98% (HPLC)

Sigma-Aldrich

SMB00460

Soyasapogenol B

Sarsasapogenin ≥98%

Sigma-Aldrich

S8534

Sarsasapogenin

Primulic acid I phyproof® Reference Substance

PHL89259

Primulic acid I

Pyronin B Dye content ≥30 %

Sigma-Aldrich

P6892

Pyronin B

Soyasaponine I phyproof® Reference Substance

PHL83545

Soyasaponine I

Digitonine Used as non-ionic detergent

Sigma-Aldrich

D141

Digitonine

Yvonne Lange et al.
Biochemistry, 48(36), 8505-8515 (2009-08-07)
A few membrane-intercalating amphipaths have been observed to stimulate the interaction of cholesterol with cholesterol oxidase, saponin and cyclodextrin, presumably by displacing cholesterol laterally from its phospholipid complexes. We now report that this effect, referred to as cholesterol activation, occurs
Isolation of myeloid and plasmacytoid dendritic cells from human bronchoalveolar lavage fluid.
Tsoumakidou M
Immunology and Cell Biology, 84(3), 267-273 (2006)
Dynamic chromatin modifications characterise the first cell cycle in mouse embryos.
Santos F
Developmental Biology, 280(1), 225-236 (2005)
R Martin-Ibañez et al.
Human reproduction (Oxford, England), 23(12), 2744-2754 (2008-08-22)
Human embryonic stem cells (hESCs) have potential use in clinical therapy and regenerative medicine. One of the major challenges regarding the application of these cells is the development of an efficient cryopreservation protocol, since current methods, which include slow-freezing-rapid thawing
Louis Lignereux et al.
Preventive veterinary medicine, 157, 70-77 (2018-08-09)
Contagious caprine pleuropneumonia (CCPP), caused by Mycoplasma capricolum subsp. capripneumoniae, has long been considered a goat-specific disease. Since 2007 there has been growing evidence that this disease can affect wild ungulates either kept in captivity or in the wild. In
Afficher tous les articles scientifiques apparentés

Notre équipe de scientifiques dispose d'une expérience dans tous les secteurs de la recherche, notamment en sciences de la vie, science des matériaux, synthèse chimique, chromatographie, analyse et dans de nombreux autres domaines..

Contacter notre Service technique