RAB0460

Human TGF-β 1 ELISA Kit

for serum, plasma, and cell culture supernatants

• Synonyme(s) : TGF-beta-1, Transforming growth factor beta-1
• NACRES: NA.32
• UNSPSC Code: 41116158
• Gene information: human ... TGFB1(7040)
• Input: sample type serum; sample type cell culture supernatant(s); sample type plasma
• Species reactivity: human
• Storage temp.: −20°C
• Shipped in: wet ice

Propriétés

• species reactivity: human
• packaging: kit of 96 wells (12 strips x 8 wells)
• technique(s): ELISA: suitable, capture ELISA: suitable
• input: sample type serum; sample type cell culture supernatant(s); sample type plasma
• assay range: inter-assay cv: <12%; intra-assay cv: <10%; sensitivity: 80 pg/mL; standard curve range: 0.0823-60 ng/mL
• detection method: colorimetric
• shipped in: wet ice
• storage temp.: −20°C
• Gene Information: human ... TGFB1(7040)

Description

General description

The Human TGF-β 1 ELISA (Enzyme-Linked mmunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of human TGF-β 1 in serum, plasma, cell culture supernatants.

Immunogen

Recombinant Human TGF-β 1

Application

For research use only. Not for use in diagnostic procedures.
Human transforming growth factor-β1 (TGF-β1) ELISA Kit has been used to measure level of TGF-β1 released from tubular cells.

Biochem/physiol Actions

Transforming growth factor-β1 (TGF-β1) is a pluripotential cytokine that plays a vital role in the homeostasis of peripheral CD4⁺CD25⁺ regulatory T cells and regulation of FOXP3 (forkhead box P3) expression in vivo. Binding of TGF-β1 to its receptor, activates members of the SMAD protein family involved in gene regulation. Study shows that reduced expression of circulating transforming growth factor-β1 (TGF-β1) might contribute to systemic lupus erythematosus (SLE) development. Polymorphism of TGF-β1 is associated with pathogenesis of rheumatoid arthritis (RA) and pneumoconiosis. Serum TGF-β1 expression is elevated in systemic sclerosis (SSc) patients. Serum TGF-β1 functions as a potential biomarker of Guillain-Barré syndrome (GBS) and SSc.

Other Notes

A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.

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Informations sur la sécurité

• pictograms: GHS05
• signalword: Warning
• hcodes: H290
• pcodes: P234 - P390
• Hazard Classifications: Met. Corr. 1
• Classe de stockage: 10 - Combustible liquids