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PVP1

Sigma-Aldrich

Poly(vinylpyrrolidone)–Iodine complex

Synonyme(s) :

PVP-Iodine, Polyvinylpyrrolidone Iodine, PVP-I, Povadyne® antiseptic

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About This Item

Numéro CAS:
25655-41-8
Numéro MDL:
MFCD00084483
Code UNSPSC :
51102829
ID de substance PubChem :
24899316
Nomenclature NACRES :
NA.85

Forme

powder

Solubilité

H2O: 100 mg/mL

Spectre d'activité de l'antibiotique

Gram-negative bacteria
Gram-positive bacteria
fungi
parasites
viruses
yeast

Mode d’action

protein synthesis | interferes

Chaîne SMILES 

II.C=CN1CCCC1=O

InChI

1S/C6H9NO.I2/c1-2-7-5-3-4-6(7)8;1-2/h2H,1,3-5H2;

Clé InChI

CPKVUHPKYQGHMW-UHFFFAOYSA-N

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Catégories apparentées

Application

Poly(vinylpyrrolidone)–Iodine complex, or PVP-I, has been used to study microbial decontamination of human donor eyes and the inactivation of infectious hematopoietic necrosis virus.

Actions biochimiques/physiologiques

PVP-1 is used as a slow iodine release formulation that iodinates lipids and oxidizes cell compounds such as tyrosine sidechains. It is used as a carbon nanotube coating agent to improve water solubility.

Autres remarques

An iodophor; "tamed iodine."
Keep container tightly closed in a dry and well-ventilated place.

Informations légales

Povadyne is a registered trademark of National Patent Development Corp.

Pictogrammes

CorrosionEnvironment
GHS05,GHS09

Mention d'avertissement

Danger

Mentions de danger

H315,H318,H411

Classification des risques

Aquatic Chronic 2 - Eye Dam. 1 - Skin Irrit. 2

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 2

Point d'éclair (°F)

>212.0 °F - Not applicable

Point d'éclair (°C)

> 100 °C - Not applicable

Équipement de protection individuelle

Eyeshields, Gloves, type N95 (US)

Certificats d'analyse (COA)

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Lawrence L Yeung et al.
The Journal of urology, 189(1), 136-140 (2012-11-21)
We defined the relevant skin flora during genitourinary prosthetic surgery, evaluated the safety of chlorhexidine-alcohol for use on the male genitalia and compared chlorhexidine-alcohol to povidone-iodine in decreasing the rate of positive bacterial skin cultures at the surgical skin site
W N Batts et al.
Applied and environmental microbiology, 57(5), 1379-1385 (1991-05-01)
The fish rhabdovirus infectious hematopoietic necrosis virus (IHNV) was rapidly inactivated by extremely low concentrations of iodine in water. A 99.9% virus reduction was obtained in 7.5 s when virus (10 PFU/ml) and iodine (0.1 mg/liter, final concentration) were combined
Ioannis Liakos et al.
Carbohydrate polymers, 92(1), 176-183 (2012-12-12)
Biodegradable polymeric materials based on blending aqueous dispersions of natural polymer sodium alginate (NaAlg) and povidone iodine (PVPI) complex, which allow controlled antiseptic release, are presented. The developed materials are either free standing NaAlg films or Ca(2+)-cross-linked alginate beads, which
E Pels et al.
The British journal of ophthalmology, 83(9), 1019-1026 (1999-08-26)
Povidone-iodine (PVP -I) is applied for microbial decontamination of human eyes donated for transplantation. Concentrations and immersion times vary greatly. The effectiveness and toxicity of PVP-I were assessed for different decontamination protocols. Human donor eyes and corneas were immersed in
Gianluca Pellino et al.
BMC surgery, 12 Suppl 1, S31-S31 (2012-11-28)
Restorative proctocolectomy with ileopouch-anal anastomosis (IPAA) is the treatment of choice for intractable or complicated ulcerative colitis(UC). Elderly patients often present with acute colitis requiring emergent subtotal colectomy(SC). Frail patients are at risk of developing septic complications related to the
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