P4651

Promethazine hydrochloride

histamine receptor antagonist, powder

• Synonyme(s) : 10-[2-(Dimethylamino)propyl]phenothiazine hydrochloride
• Formule empirique (notation de Hill) : C₁₇H₂₀N₂S · HCl
• Numéro CAS: 58-33-3
• Poids moléculaire : 320.88
• NACRES: NA.77
• PubChem Substance ID: 24277802
• UNSPSC Code: 12352200
• EC Number: 200-375-2
• MDL number: MFCD00012652
• Beilstein/REAXYS Number: 4166397
• Form: powder

Propriétés

• Nom du produit: Promethazine hydrochloride,
• form: powder
• Quality Segment: 200
• originator: Wyeth
• storage temp.: 2-8°C
• SMILES string: Cl[H].CC(CN1c2ccccc2Sc3ccccc13)N(C)C
• InChI: 1S/C17H20N2S.ClH/c1-13(18(2)3)12-19-14-8-4-6-10-16(14)20-17-11-7-5-9-15(17)19;/h4-11,13H,12H2,1-3H3;1H
• InChI key: XXPDBLUZJRXNNZ-UHFFFAOYSA-N
• Gene Information: human ... HRH1(3269)

Description

Biochem/physiol Actions

H₁ histamine receptor antagonist; CNS depressant; anticholinergic.

Features and Benefits

This compound was developed by Wyeth. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Physical form

Appearance: White or faint yellow, odorless, Crystalline powder, slowly oxidizes and acquires a blue color, on prolonged exposure to air.

Other Notes

Solubility: Freely soluble in water, in hot dehydrated alcohol and in Chloroform. Practically insoluble in ether, in acetone and in ethyl acetate.

Informations sur la sécurité

• pictograms: GHS05,GHS07,GHS09
• signalword: Danger
• hcodes: H302,H317,H318,H411
• pcodes: P261 - P273 - P280 - P301 + P312 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Skin Sens. 1
• Classe de stockage: 11 - Combustible Solids
• wgk: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Faceshields, Gloves