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Merck
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P1411

Sigma-Aldrich

Polymyxin B-Agarose

aqueous glycerol suspension

Synonyme(s) :

PMB

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About This Item

Numéro MDL:
MFCD00165491
Code UNSPSC :
41106500
Nomenclature NACRES :
NA.56

Source biologique

synthetic (organic)

Niveau de qualité

200

Forme

aqueous glycerol suspension

Ampleur du marquage

~1 mg per mL

Technique(s)

affinity chromatography: suitable

Matrice

Cross-linked 4% beaded agarose

Activation de la matrice

cyanogen bromide

Fixation de matrice

amino

Espaceur de matrice

1 atom

Capacité

200-500 μg/mL binding capacity (lipopolysaccharide)(from Escherichia coli serotype 0128:B12)

Adéquation

suitable for chromatography

Température de stockage

2-8°C

Application

Polymyxin B-agarose is used in protein chromatography, affinity chromatography and specialty resins. Polymyxin B-agarose has been used to study periodontitis and endodontic infections as well as obesity and type 2 diabetes.
Useful for removal of endotoxins from solutions

Forme physique

Suspension in 50% glycerol containing 0.02% sodium azide

Code de la classe de stockage

10 - Combustible liquids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

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Certificats d'analyse (COA)

Lot/Batch Number
0000375992
0000364940
0000348645
0000375992
0000364940

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Martín López et al.
Journal of immunology (Baltimore, Md. : 1950), 170(5), 2409-2416 (2003-02-21)
Macrophages infected with Mycobacterium tuberculosis undergo increased rates of apoptosis. Important objectives are to define the microbial factors that cause apoptosis, the mechanisms involved and the impact on infection. The 19-kDa M. tuberculosis glycolipoprotein (p19) is both cell wall-associated and
A C Issekutz
Journal of immunological methods, 61(3), 275-281 (1983-07-29)
Endotoxins liberated by gram-negative bacteria are frequent contaminants of aqueous and physiological solutions. Because of their potent biological effects in vivo and in vitro, it is often necessary to eliminate even minute quantities of endotoxin from such solutions. A process
Samira B R Prado et al.
Scientific reports, 10(1), 1690-1690 (2020-02-06)
Dietary fibers have been shown to exert immune effects via interaction with pattern recognition receptors (PRR) such as toll-like receptors (TLR) and nucleotide-binding oligomerization domain (NOD)-like receptors. Pectin is a dietary fiber that interacts with PRR depending on its chemical
K Stuhlmeier et al.
Clinical and experimental immunology, 84(2), 317-323 (1991-05-01)
Coumarin as well as its derivatives 7-OH coumarin and 4-OH coumarin were found to stimulate interleukin-1 beta (IL-1 beta) release from freshly isolated human mononuclear cells (MNC) if the culture medium contained fetal calf serum. Under serum-free conditions, almost no
C Moreno et al.
Clinical and experimental immunology, 76(2), 240-245 (1989-05-01)
We show here that purified lipoarabinomannan (LAM) from Mycobacterium tuberculosis can cause the release of tumour necrosis factor (TNF) in vitro from human blood monocytes and activated mouse peritoneal macrophages, and the production of TNF in vivo in mice pretreated
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