MAK152
Colorimetric Sphingomyelinase Assay Kit
sufficient for 200 colorimetric tests
Synonyme(s) :
Neutral Sphingomyelinase Assay Kit
Se connecter pour consulter les tarifs organisationnels et contractuels.
Sélectionner une taille de conditionnement
Changer de vue
A propos de cet article
NACRES:
NA.84
UNSPSC Code:
12161503
Service technique
Besoin d'aide ? Notre équipe de scientifiques expérimentés est là pour vous.
Laissez-nous vous aiderusage
sufficient for 200 colorimetric tests
detection method
colorimetric
relevant disease(s)
rheumatological diseases; cancer
storage temp.
−20°C
Gene Information
human ... SMPD2(6610), SMPD3(55512), SMPD4(55627)
mouse ... SMPD2(20598), SMPD3(58994), SMPD4(77626)
rat ... SMPD2(83537), SMPD3(94338), SMPD4(303790)
General description
Sphingomyelinase (SMase), or sphingomyelin phosphodiesterase, catalyzes the hydrolytic cleavage of sphingolipid to phosphocholine and ceramide, a second messenger involved in multiple cellular responses including the cellular response to stress. There are at least 5 types of SMases identified which are classified according to their cation dependence, cellular location, and pH optima for activity and include the acidic and neutral sphingomyelinase. Neutral SMases, along with the acidic SMases, are thought to be major contributors to the production of ceramide in response to cellular stress.
Application
This kit is suitable for the detection of sphingomyelinase activity in a variety of samples such as blood and cell extracts or for screening sphingomyelinase inhibitors and activators.
Biochem/physiol Actions
The Sphingomyelinase Assay Kit provides a simple and direct procedure for measuring neutral SMase activity in a variety of samples such as blood or cell extracts, or for screening SMase activators and inhibitors. SMase activity is determined by a coupled enzyme assay, which results in a colorimetric (655 nm) product proportional to the SMase activity present.
Features and Benefits
Compatible with high-throughput handling systems.
Mot-clé
Danger
Classe de stockage
10 - Combustible liquids
Que se passe-t-il ?
WGK 3
Codes de danger
Mentions de précaution
Hazard Classifications
Aquatic Acute 1 - Aquatic Chronic 2 - ED ENV 1 - Eye Dam. 1 - Resp. Sens. 1
Faites votre choix parmi les versions les plus récentes :
Déjà en possession de ce produit ?
Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.