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Key Documents

M9130

Sigma-Aldrich

4-Méthylumbelliféryl-β-D-glucuronide hydrate

≥98% (HPLC), BioReagent, for identification of transformed plants

Synonyme(s) :

Acide 4-méthylumbelliféryl-β-D-glucopyranosiduronique, MUG

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About This Item

Formule empirique (notation de Hill):
C16H16O9 · xH2O
Numéro CAS:
Poids moléculaire :
352.29 (anhydrous basis)
Numéro MDL:
Code UNSPSC :
12352200
ID de substance PubChem :
Nomenclature NACRES :
NA.52

Qualité

for molecular biology

Gamme de produits

BioReagent

Pureté

≥98% (HPLC)

Forme

powder

Solubilité

pyridine: 50 mg/mL, clear, colorless to very faintly yellow

Température de stockage

−20°C

Chaîne SMILES 

O.CC1=CC(=O)Oc2cc(O[C@@H]3O[C@@H]([C@@H](O)[C@H](O)[C@H]3O)C(O)=O)ccc12

InChI

1S/C16H16O9.H2O/c1-6-4-10(17)24-9-5-7(2-3-8(6)9)23-16-13(20)11(18)12(19)14(25-16)15(21)22;/h2-5,11-14,16,18-20H,1H3,(H,21,22);1H2/t11-,12-,13+,14-,16+;/m0./s1

Clé InChI

URVSQZMOFUEQAW-YYHOVTOASA-N

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Description générale

MUG is a chemical commonly used for the detection of transformed plants. MUG shows low levels of fluorescence until treatment with glucuronidase (GUS) encoded in transformed plants. Transformed plants can be identified by their MUG fluorescence.

Application

Suitable for fluorescent detection of glucuronidase gene expression in plants.

Reconstitution

Product is soluble in molecular biology grade water at a concentration of 0.35 mg/ml.

Produit(s) apparenté(s)

Réf. du produit
Description
Tarif

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

Eyeshields, Gloves, type N95 (US)


Certificats d'analyse (COA)

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Consulter la Bibliothèque de documents

L J Moberg
Applied and environmental microbiology, 50(6), 1383-1387 (1985-12-01)
An assay procedure to screen for Escherichia coli in foods by using 4-methylumbelliferyl-beta-D-glucuronide (MUG) incorporated into lauryl tryptose (LST) broth was evaluated. The beta-glucuronidase produced by E. coli cleaves the MUG substrate to yield a fluorescent end product. E. coli-negative
Andrew G Kunihiro et al.
Molecular nutrition & food research, 64(14), e2000072-e2000072 (2020-06-09)
Curcumin prevents bone loss in resorptive bone diseases and inhibits osteoclast formation, a key process driving bone loss. Curcumin circulates as an inactive glucuronide that can be deconjugated in situ by bone's high β-glucuronidase (GUSB) content, forming the active aglycone.
Yuan Ruan et al.
Current biology : CB, 28(17), 2718-2729 (2018-08-28)
The capacity for sustained cell division within the plant meristem is a critical determinant of organ structure and performance. This capacity is diminished in mutants lacking the microtubule-associated protein CLASP and when brassinosteroid signaling is increased. Here, we discovered that
Xiaotian Zhong et al.
The Journal of biological chemistry, 295(10), 3115-3133 (2020-02-02)
The fortuitously discovered antiaging membrane protein αKlotho (Klotho) is highly expressed in the kidney, and deletion of the Klotho gene in mice causes a phenotype strikingly similar to that of chronic kidney disease (CKD). Klotho functions as a co-receptor for
M C Thaller et al.
Journal of clinical microbiology, 26(4), 791-793 (1988-04-01)
A new selective, differential plating medium to screen the common gram-negative urinary tract pathogens is described. The medium combines adonitol fermentation, phenylalanine deaminase, and beta-glucuronidase tests and allows the indole and cytochrome oxidase tests to be performed directly from the

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