M9024

MOPS sodium salt

BioPerformance Certified, suitable for cell culture, ≥99.5%

• Synonyme(s) : Acide 3-(N-morpholino)propanesulfonique sodium salt, Acide 4-morpholinepropanesulfonique sodium salt
• Formule empirique (notation de Hill) : C₇H₁₄NNaO₄S
• Numéro CAS: 71119-22-7
• Poids moléculaire : 231.25
• NACRES: NA.25
• PubChem Substance ID: 24897311
• UNSPSC Code: 12161700
• MDL number: MFCD00064350

Propriétés

• grade: BioPerformance Certified
• Quality Segment: 400
• assay: ≥99.5%
• form: powder
• technique(s): cell culture | mammalian: suitable
• impurities: endotoxin and bioburden, tested
• useful pH range: 6.5-7.9
• pKa (25 °C): 7.2
• anion traces: ≤0.0005% (Lead (Pb))
• suitability: suitable for determination of protein concentration
• application(s): diagnostic assay manufacturing
• foreign activity: DNase, RNase, NICKase and protease, none detected
• SMILES string: [Na+].[O-]S(=O)(=O)CCCN1CCOCC1
• InChI: 1S/C7H15NO4S.Na/c9-13(10,11)7-1-2-8-3-5-12-6-4-8;/h1-7H2,(H,9,10,11);/q;+1/p-1
• InChI key: MWEMXEWFLIDTSJ-UHFFFAOYSA-M

Description

General description

MOPS is a morpholino propanesulfonic acid sodium salt, a structural analog to MES, the ethanesulfonic acid (first introduced by Good et al.), developed to meet the following criteria: midrange pKa, maximum water solubility and minimum solubility in all other solvents, minimal salt effects, minimal change in pK a with temperature, chemically and enzymatically stable, minimal absorption in visible or UV spectral range and reasonably easily synthesized.

Application

• Buffers more than buffering agent: introducing a new class of stabilizers for the protein BSA.: This research highlights the use of MOPS sodium salt as a novel stabilizing agent for bovine serum albumin (BSA), extending its role beyond a simple buffering agent. The study demonstrates how MOPS sodium salt can improve the stability of BSA under various conditions, providing significant insights for biochemical applications and protein preservation (Gupta BS et al., 2015).

Features and Benefits

Features:

1. Qualified Raw Materials: Products that meet the stringent requirements of the Elevated Assurance Program, ensuring compliance with regulatory standards.
2. Comprehensive Documentation: Includes essential documents such as certificates, impurity profiles, and declarations to support audits and risk assessments.
3. M-Clarity^™ Quality Attributes: Products are classified within the MQ300 quality segment or higher, demonstrating superior quality assurance. M-Clarity^™ Program
4. Confirmed Process Controls: Established processes that ensure consistency and reliability in manufacturing.
5. Enhanced Change Notification: Timely updates on any changes to product specifications or processes, ensuring transparency and compliance.
6. Freely Available Dossiers: Access to robust, ready-to-present product dossiers that include:
   1. Site quality assessment
   2. ISO 9001 certificate
   3. Detailed product specifications
   4. Relevant declarations/statements (e.g., animal origin content, BSE/TSE, nitrosamine)

Benefits:

1. Regulatory Compliance: Helps you meet compliance standards effectively, reducing the risk of regulatory issues.
2. Audit Readiness: Instills confidence during audits with comprehensive documentation and confirmed process controls, demonstrating your commitment to high-quality products.
3. Operational Transparency: Supports supply chain transparency, allowing you to track and verify the quality of raw materials.
4. Enhanced Support: Provides exceptional quality-related information and tailored assistance to meet your specific needs.
5. Risk Mitigation: Facilitates thorough risk assessments with detailed documentation, helping you manage potential compliance challenges.
6. Informed Decision-Making: Access to clear and comprehensive product information enables better decision-making and enhances operational efficiency.

Other Notes

Easily compare specifications for MOPS sodium salt products with the MOPS sodium salt specification table.

Legal Information

M-CLARITY is a trademark of Merck KGaA, Darmstadt, Germany

Informations sur la sécurité

• Classe de stockage: 13 - Non Combustible Solids
• Que se passe-t-il ?: WGK 1
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• EPI (équipement de protection individuelle): Eyeshields, Gloves, type N95 (US)