H5388

Hyaluronic acid sodium salt from rooster comb

avian glycosaminoglycan polysaccharide

• Synonyme(s) : Poly(β-glucuronic acid-[1→3]-β-N-acetylglucosamine-[1→4]), alternating
• Numéro CAS: 9067-32-7
• UNSPSC Code: 12352201
• PubChem Substance ID: 24895688
• NACRES: NA.25
• MDL number: MFCD01773053

Propriétés

• biological source: chicken (rooster comb)
• Quality Segment: 200
• form: powder
• impurities: ≤2% protein (Lowry)
• color: white
• solubility: water: ~5 g/L
• cation traces: Na: 3-7%
• storage temp.: −20°C
• SMILES string: [Na+].N([C@H]1[C@@H](O[C@@H]([C@H]([C@@H]1O[C@@H]4O[C@@H]([C@H]([C@@H]([C@H]4O)O)O)C(=O)O)O)CO)O[C@@H]2[C@H](O[C@H]([C@@H]([C@H]2O)O)O[C@@H]3[C@H]([C@@H](O[C@@H]([C@H]3O)CO)O)NC(=O)C)C(=O)O)C(=O)C
• InChI: 1S/C28H44N2O23.Na/c1-5(33)29-9-18(11(35)7(3-31)47-25(9)46)49-28-17(41)15(39)20(22(53-28)24(44)45)51-26-10(30-6(2)34)19(12(36)8(4-32)48-26)50-27-16(40)13(37)14(38)21(52-27)23(42)43;/h7-22,25-28,31-32,35-41,46H,3-4H2,1-2H3,(H,29,33)(H,30,34)(H,42,43)(H,44,45);/q;+1/t7-,8-,9-,10-,11-,12-,13+,14+,15-,16-,17-,18-,19-,20+,21+,22+,25-,26+,27-,28-;/m1./s1
• InChI key: YWIVKILSMZOHHF-QJZPQSOGSA-N

Description

Application

Hyaluronic acid sodium salt from rooster comb has been used:

• as a component of bi-layer gelatin scaffold
• as a vehicle for release of gentamicin during left ear surgery in guinea pigs
• in hyaluronic acid binding assay in human embryonic kidney cell line 293T

Biochem/physiol Actions

Hyaluronic acid is a polysaccharide present in the skin, connective tissue, vitreous humor and synovial fluid. It is essential for tissue hydration and functions to regenerate skin post injury or wounds. Hyaluronic acid, apart from having dermatologic and ophthalmologic applications, serves as a drug delivery vehicle. Hyaluronic acid also exhibits antioxidant and antiglycation properties.

High molecular mass polymer composed of repeating dimeric units of glucuronic acid and N-acetyl glucosamine which forms the core of complex proteoglycan aggregates found in extracellular matrix.

Other Notes

To gain a comprehensive understanding of our extensive range of Polysaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Informations sur la sécurité

• Classe de stockage: 11 - Combustible Solids
• wgk: WGK 2
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves