F9926

FIM-1

≥99% purity (TLC), powder

• Synonyme(s) : N-[3-(3-[2,5-Dihydro-4-(1-methyl-1H-indol-3-yl)-2,5-dioxo-1H-pyrrol-3-yl]-1H-indol-1-yl)propyl]-3′,6′-dihydroxy-3-oxospiro[isobenzofuran-1[3H],9′-[9H]xanthene]-5-carboxamide
• Formule empirique (notation de Hill) : C₄₅H₃₁N₄O₈
• Numéro CAS: 220518-50-3
• Poids moléculaire : 755.75
• UNSPSC Code: 12171500
• PubChem Substance ID: 329799791
• NACRES: NA.47
• MDL number: MFCD03453075

Propriétés

• Nom du produit: FIM-1,
• assay: ≥99% (TLC)
• Quality Segment: 200
• form: powder
• color: red
• solubility: DMSO or DMF: soluble
• εmax: 81.8 at 486 nm in methanol
• application(s): diagnostic assay manufacturing; hematology; histology
• shipped in: dry ice
• storage temp.: −20°C
• SMILES string: Cn1c(cc2ccccc12)C3=C(C(=O)NC3=O)c4cn(CCCNC(=O)c5ccc6c(c5)C(=O)OC67c8ccc(O)cc8Oc9cc(O)ccc79)c%10ccccc4%10
• InChI: 1S/C45H32N4O8/c1-48-34-9-4-2-7-24(34)20-36(48)40-39(42(53)47-43(40)54)30-23-49(35-10-5-3-8-28(30)35)18-6-17-46-41(52)25-11-14-31-29(19-25)44(55)57-45(31)32-15-12-26(50)21-37(32)56-38-22-27(51)13-16-33(38)45/h2-5,7-16,19-23,50-51H,6,17-18H2,1H3,(H,46,52)(H,47,53,54)
• InChI key: WZJAWTNAOLZZOO-UHFFFAOYSA-N

Description

Biochem/physiol Actions

A fluorescent conjugate of bisindolylmaleimide that specifically binds phosphokinase C at the active site. Can monitor enzyme activation and translocation. This reagent is not membrane permeable. The diacetate form (Sigma No. F9801) is membrane permeable.

Informations sur la sécurité

• Classe de stockage: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)