F9677

Felodipine

L-type calcium channel blocker, solid

• Synonyme(s) : 4-(2,3-Dichlorophenyl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinecarboxylic acid ethyl methyl ester, Plendil
• Formule empirique (notation de Hill) : C₁₈H₁₉NO₄Cl₂
• Numéro CAS: 72509-76-3
• Poids moléculaire : 384.25
• UNSPSC Code: 12352200
• PubChem Substance ID: 24278449
• NACRES: NA.77
• MDL number: MFCD00868316
• Form: solid

Propriétés

• Nom du produit: Felodipine, solid
• form: solid
• Quality Segment: 200
• solubility: DMSO: 20 mg/mL, H₂O: insoluble
• originator: AstraZeneca
• SMILES string: CCOC(=O)C1=C(C)NC(C)=C(C1c2cccc(Cl)c2Cl)C(=O)OC
• InChI: 1S/C18H19Cl2NO4/c1-5-25-18(23)14-10(3)21-9(2)13(17(22)24-4)15(14)11-7-6-8-12(19)16(11)20/h6-8,15,21H,5H2,1-4H3
• InChI key: RZTAMFZIAATZDJ-UHFFFAOYSA-N
• Gene Information: human ... CACNA1C(775), CACNA1D(776), CACNA1F(778), CACNA1S(779), CACNA2D1(781), NR3C2(4306)

Description

General description

Felodipine is a dihydropyridine derivative. It has diuretic properties. Felodipine has high vascular selectivity. It is used to treat hypertension. Felodipine regulates chronic stable angina.

Biochem/physiol Actions

L-type calcium channel blocker

Features and Benefits

This compound was developed by AstraZeneca. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Informations sur la sécurité

• pictograms: GHS08,GHS07,GHS09
• signalword: Warning
• hcodes: H302,H361d,H373,H410
• pcodes: P202 - P260 - P264 - P273 - P301 + P312 - P308 + P313
• Hazard Classifications: Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Repr. 2 - STOT RE 2 Inhalation
• Classe de stockage: 11 - Combustible Solids
• wgk: WGK 3
• ppe: dust mask type N95 (US), Eyeshields, Gloves